Circular RNAs (circRNAs) are covalently closed non-coding RNAs formed by back-splicing, lacking a 5' cap and poly-A tail. They could act as important regulatory factors in the host's anti-tuberculosis immune process, but only a few have been identified, and their molecular mechanisms remain largely unclear. Here, we identified a novel circRNA, circ-ZNF277, which responds to () infection in THP-1 cells.
View Article and Find Full Text PDFCompared to mechanical ones, liquid crystal (LC) beam deflectors present several advantages, such as non-mechanical control, compactness, and low power consumption, making them a viable alternative. In this work, we demonstrate an LC-based polarization-dependent, electrically tunable beam deflector, which is a composite blazed grating fabricated using a single-step photopolymerization-induced phase separation (PIPS) technique. We investigated the effect of different factors on the performance of the deflector, including the thickness of the upper substrate, the grating period, and the cell gap.
View Article and Find Full Text PDFWe propose an innovative design for interdigital transducers (IDTs), enabling phase modulation of surface acoustic waves (SAWs) with a dislocated electrode structure. By designing the size and arrangement of these dislocated IDTs, a novel type of Airy SAWs can be generated, exhibiting self-accelerating, self-bending, and self-healing characteristics. The acceleration of the generated Airy SAW is 0.
View Article and Find Full Text PDFStimuli-responsive materials have garnered substantial interest in recent years, particularly liquid crystal networks (LCNs) with sophisticatedly designed structures and morphing capabilities. Extensive efforts have been devoted to LCN structural designs spanning from two-dimensional (2D) to three-dimensional (3D) configurations and their intricate morphing behaviors through designed alignment. However, achieving microscale structures and large-area preparation necessitates the development of novel techniques capable of facilely fabricating LCN microstructures with precise control over both overall shape and alignment, enabling a 3D-to-3D shape change.
View Article and Find Full Text PDFConventionally, the fabrication of liquid crystal lenticular microlens arrays (LCLMLAs) is complicated and costly. Here, we demonstrate a one-step fabrication technique for LCLMLAs, which is prepared through the photopolymerization-induced phase separation in the LC/polymer composite. The LCLMLAs possess both polarization-dependent and electrically tunable focusing properties.
View Article and Find Full Text PDFCircular RNAs (circRNAs) are noncoding RNAs with diverse functions. However, most ()-related circRNAs remain undiscovered. In this study, we infected THP-1 cells with virulent and avirulent strains and then sequenced the cellular circRNAs.
View Article and Find Full Text PDFDue to the unique self-acceleration, self-healing, and non-diffraction properties, Airy beams have been explored extensively and found applications in various fields. It has been proven as an essential aspect to tune the trajectory of Airy beams for extensive applications. In this paper, we propose a method based on liquid crystal (LC) alignment with metasurfaces, which enables dynamic tuning of the trajectory of Airy beams.
View Article and Find Full Text PDFMetasurfaces can enable polarization multiplexing of light so as to carry more information. Specific polarized light necessitates bulk polarizers and waveplates, which significantly increases the form size of metasurface devices. We propose an electrically programmable metasurface enabled by dual-frequency cholesteric liquid crystals (DF-CLCs) for simultaneous near- and far-field displays.
View Article and Find Full Text PDFChirality induction, transfer, and manipulation have aroused great interest in achiral nanomaterials. Here, we demonstrate strong upconverted circularly polarized luminescence from achiral core-shell upconversion nanoparticles (UCNPs) via a plasmonic chiral metasurface-induced optical chirality transfer. The Yb-sensitized core-shell UCNPs with good dispersity exhibit intense upconversion luminescence of Tm and Nd through the energy transfer process.
View Article and Find Full Text PDFMycoplasmas as economically important and pantropic pathogens can cause similar clinical diseases in different hosts by eluding host defense and establishing their niches despite their limited metabolic capacities. Besides, enormous undiscovered virulence has a fundamental role in the pathogenesis of pathogenic mycoplasmas. On the other hand, they are host-specific pathogens with some highly pathogenic members that can colonize a vast number of habitats.
View Article and Find Full Text PDFNanomaterials (Basel)
April 2022
Surface-enhanced Raman spectroscopy (SERS) has long been an ultrasensitive technique for trace molecule detection. However, the development of a sensitive, stable, and reproducible SERS substrate is still a challenge for practical applications. Here, we demonstrate a cost-effective, centimeter-sized, and highly reproducible SERS substrate using the nanosphere lithography technique.
View Article and Find Full Text PDFFront Cell Infect Microbiol
June 2021
() can survive in the hostile microenvironment of cells by escaping host surveillance, but the molecular mechanisms are far from being fully understood. MicroRNAs might be involved in regulation of this intracellular process. By RNAseq of -infected PMA-differentiated THP-1 macrophages, we previously discovered down-regulation of miR-378d during infection.
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