Publications by authors named "Dekuang Yu"

Purpose: Speed estimation of drivers' own vehicles and other vehicles on the road is an important task for drivers and is also crucial to the roadway safety. The objective of the study was to examine the effects of multiple factors such as image scale, speed, road type, driving experience, and gender on the speed perception of drivers' own vehicles.

Methods: Thirty participants consisted of 17 males and 13 females, including 13 without driving experience.

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B-type ultrasound images have important applications in medical diagnosis. However, the widely spread intensity inhomogeneity, low-scale contrast, constructed defect, noise and blurred edges all make it difficult to implement automatic segmentation of lesion in the images. Based on region level set method, a subordinate degree region level set model was proposed, in which subordinate degree probability of each pixel was defined to reflect the pixel subjection grade to target and background respectively.

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Objective: To modify the level set method for precise and fast segmentation of B-type ultrasound image lesions.

Methods: Based on the best of region level set method, entropy in the information theory was introduced into image processing to define a dynamic weighting factor that responded to the gradient change of the local gray levels to evaluate the dynamic degree of driven force on each pixel on the contour to the target and background areas. The dynamic weighting factors were reconciled into the regional level set model and led the contour to deform and move during the iterations.

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Purpose: There is a need for automated retinal optical coherence tomography (OCT) image analysis tools for quantitative measurements in small animals. Some image processing techniques for retinal layer analysis have been developed, but reports about how useful those techniques are in actual animal studies are rare. This paper presents the use of a retinal layer detection method we developed in an actual mouse study that involves wild type and mutated mice carrying photoreceptor degeneration.

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Purpose: To characterize the microbead-induced ocular hypertension (OHT) mouse model and investigate its potential use for preclinical screening and evaluation of ocular hypotensive agents, we tested the model's responses to major antiglaucoma drugs.

Methods: Adult C57BL/6J mice were induced to develop OHT unilaterally by intracameral injection of microbeads. The effects of the most commonly used ocular hypotensive drugs, including timolol, brimonidine, brinzolamide, pilocarpine, and latanoprost, on IOP and glaucomatous neural damage were evaluated.

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In addition to many other genes, tissue-specific genes (TSGs) represent a set of genes of great importance for human physiology. However, the links among TSGs, diseases, and potential therapeutic agents are often missing, hidden, or too scattered to find. There is a need to establish a knowledgebase for researchers to share this and additional information in order to speed up discovery and clinical practice.

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Objective: To compare the value of head-chest lead electrocardiogram (HCECG) and routine lead electrocardiogram (RLECG) in diagnosis of acute positive posterior myocardial infarction.

Methods: HCECGs and RLECGs were recorded simultaneously in 68 normal individuals and 32 patients with acute posterior wall myocardial infarction confirmed by coronary angiography and echocardiography. Each HCECG and RLECG was analyzed by two senior physicians specialized in clinical electrophysiology who were blinded to the results.

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Conventional medical experiments can hardly simulate cardiac excitation propagation and observe the evolvement of cardiac electrical activities firsthand as is possible with computer simulation. Based on the anatomic structure of the heart, simulation of cardiac electrical activity mainly consists of the emulation of the excitation process among the cardiac cells and calculation of the electrical activities of individual cardiac cells. In this study we establish a geometric ventricular structure model demonstrating the direction of the cardiac muscle fibers and the layers of the ventricular cells, and endow different action potential models to the ventricular cells of different layers, and observe the activation process of the ventricular parts in view of the three-dimensional anatomy.

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The interference by 50-Hz noise arising from the power supply cables is common in PC-based application system, often considerably affecting the detection of useful signals. On the basis of self-adapting correlation method, we attempt to address the problem of fast elimination of 50-Hz noise from the useful signals in PC-based application system such as digital ECG recording system.

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Objective: To define the distribution of the cardiac electric field around the isolated heart of guinea pig.

Methods: The hearts of 26 guinea pigs were isolated and immersed in normal saline or distilled water, and the ECGs were recorded in 4 directions of every plane with 4 points deposited in every direction at different distances from the anterior, posterior and the laterals of both the ventricles of the heart.

Result: In both media, ECGs were composed mainly of upright waves were recorded at all points in the 4 directions at the 3 levels.

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