Thalidomide as Treatment of Lip's Pyogenic Granuloma.

Pyogenic granuloma (PG) is a benign vascular tumor that can be challenging to treat, particularly in aesthetically sensitive areas. We report a case of a 32-year-old man with a PG on the upper lip that did not respond to conventional treatments, including glucocorticoid injections and long-pulse 1064 nm laser therapy. Due to aesthetic concerns and the lack of response to these treatments, the patient was administered oral thalidomide at a nightly dose of 75 mg for 5 months, which resulted in complete regression without recurrence over a 3-year follow-up.

Acute effects of different Tai Chi practice protocols on cardiac autonomic modulation.

Tai Chi serves as an effective exercise modality for enhancing autonomic regulation. However, a majority of existing studies have employed the single routine (SR) protocol as the basis for health interventions. The extent to which the gong routine application (GRA) protocol achieves similar levels of exercise load stimulation as traditional single practice routines remains uncertain.

Involvement of cAMP receptor protein in biofilm formation, fimbria production, capsular polysaccharide biosynthesis and lethality in mouse of Klebsiella pneumoniae serotype K1 causing pyogenic liver abscess.

The global regulator cAMP receptor protein (CRP) has been shown to be required for the full virulence and/or for the expression of virulence determinants in a wide set of bacterial pathogens. In this work, the crp mutant as well as the complemented mutant was constructed from a wild-type Klebsiella pneumoniae capsular serotype K1 strain causing the primary pyogenic liver abscess. The phenotypes of wild-type strain, crp mutant and complemented mutant were characterized systematically.

[Purification and identification of recombinant varicella-zoster virus glycoprotein E].

Objective: To purify and identify recombinant Varicella-Zoster Virus Glycoprotein E.

Methods: The recombinant plasmid pGEX-VZVgE was induced by isopropyl-beta-D-thiogalactoside (IPTG), the fusion protein was purified with affinity chromatography column; then the purified fusion protein was cleaved by thrombin, and the product's antigenicity was examined by Western blot.

Results: The product of pGEX-VZVgE induced by IPTG was separated from the mixture proteins by the affinity chromatography column, the expressed fusion protein's relative molecular mass was about 98 x 10(3).