Drug use in pregnancy in Ireland's capital city: A decade of trends and outcomes.

Objective: The aim of this study was to present contemporary trends in opiate use disorder (OUD) and substance use in pregnancy in Ireland, with associated obstetric outcomes, over the last ten years.

Study Design: This retrospective observational cohort study was conducted at an Irish tertiary maternity unit. All women with OUD or substance use in pregnancy delivered under this service between 2010 and 2019 were included.

Methadone dosing and prescribed medication use in a prospective cohort of opioid-dependent pregnant women.

Aims: This study aimed to (i) describe methadone dosing before, during and after pregnancy, (ii) to compare the incidence of neonatal abstinence syndrome (NAS) between those with dose decreases and those with steady or increasing doses and (iii) to describe prescribed medication use among opioid-dependent pregnant women.

Design: Prospective cohort study.

Setting: Two Irish tertiary care maternity hospitals.

Methadone and perinatal outcomes: a prospective cohort study.

Aims:   Methadone use in pregnancy has been associated with adverse perinatal outcomes and neonatal abstinence syndrome (NAS). This study aimed to examine perinatal outcomes and NAS in relation to (i) concomitant drug use and (ii) methadone dose.

Design:   Prospective cohort study.