Publications by authors named "Dehui Li"

Mastering the surface chemistry of quantum dots (QDs) has enabled a remarkable gas-sensing response as well as impressive air stability. To overcome the intrinsic receptor-transducer mismatch of QDs, PbS QDs used as sensitive NO receptors are spin-coated on top of a few-layer MoS and incorporated into a thin-film transistor (TFT) gas sensor. This architecture enables the separation of the electron transduction function from the chemical reception function.

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This manuscript used network pharmacology and experimental verification to analyze the anti-hepatocarcinoma mechanism of action of bezoars in traditional Chinese medicine (TCM), discovering that it can affect the immune cells within the tumor microenvironment and related pathways to produce inhibitory effects in liver cancer. In TCM, bezoars have a unique therapeutic advantage in the prevention and treatment of tumors. They play an anti-tumorigenic role by regulating the immune microenvironment through multi-component, multi-target and multi-pathway mechanisms.

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The poultry industry struggles with oxidative stress affecting gut health and productivity. This study examined using 1-Deoxynojirimycin (DNJ) extracts from mulberry leaves as an antioxidant in broilers feed to combat this issue. We divided 240 broilers, aged 16 days, into six groups, including a control and groups exposed to oxidative stress through HO injections, with different supplement levels of DNJ-E (40, 80, 120, and 160 mg/kg of the basal diet) lasting until the broilers reached 42 days old.

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Host immunity and autophagy of cancer cells markedly impact the development of gastric cancer. Hua-Zhuo-Jie-Du decoction (TDP) has been used in gastritis clinically. This study aimed to evaluate the effects of TDP combined with cisplatin (DDP) on gastric cancer and explore the molecular mechanism.

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Article Synopsis
  • Lung cancer has a poor prognosis, but recent studies suggest that inducing ferroptosis, a form of cell death, could be a promising treatment approach.
  • This study specifically investigates oleic acid (OA), the main component of Brucea javanica oil (BJO), and its effects on lung cancer cell lines A549 and H1299.
  • Findings indicate that OA inhibits cancer cell growth and migration, suppresses SDC4 expression, and promotes ferroptosis by altering the levels of several key proteins involved in this process, highlighting its potential for lung cancer therapy.
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This review comments on the article "To explore the mechanism of Yigong San anti-gastric cancer and immune regulation". We are interested that the article applied network pharmacology and bioinformatics techniques to elucidate the mechanism of action of Yigong Sang, a traditional Chinese medicine (TCM), in the treatment of gastric cancer (GC). The mechanism of action of Yigong Sang in the treatment of GC has not yet been elucidated because it is composed of multiple Chinese medicines with multiple components and multiple targets.

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Lead-free halide double perovskite (HDP) CsAgBiBr has set a benchmark for research in HDP photoelectric applications due to its attractive optoelectronic properties. However, its narrow absorption range is a key limitation of this material. Herein, a novel dopant, palladium (Pd), is doped into CsAgBiBr and significantly extends the absorption to ≈1400 nm.

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Background: Organizing pneumonia secondary to pulmonary tuberculosis is rare. Moreover, the temporal boundary between pulmonary tuberculosis and secondary organizing pneumonia has not been defined. We report a case of secondary organizing pneumonia associated with pulmonary tuberculosis occurring after nine months of antituberculosis treatment.

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Article Synopsis
  • Breast cancer is a prevalent and increasingly common malignant tumor in women, with triple-negative breast cancer (TNBC) being a particularly aggressive subtype that poses significant treatment challenges.
  • TNBC lacks key hormone receptors, leading to higher rates of metastasis and recurrence, and historically has been primarily treated with chemotherapy.
  • Recent advancements in immunotherapy have introduced new treatment options for TNBC, including immune checkpoint inhibitors and tumor vaccines, offering fresh hope in managing this difficult-to-treat cancer.
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Chiral inorganic semiconductors with high dissymmetric factor are highly desirable, but it is generally difficult to induce chiral structure in inorganic semiconductors because of their structure rigidity and symmetry. In this study, we introduced chiral ZnO film as hard template to transfer chirality to CsPbBr film and PbS quantum dots (QDs) for circularly polarized light (CPL) emission and detection, respectively. The prepared CsPbBr/ZnO thin film exhibited CPL emission at 520 nm and the PbS QDs/ZnO film realized CPL detection at 780 nm, featuring high dissymmetric factor up to around 0.

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We report a zero-dimensional (0D) lead-free chiral perovskite (S-/R-MBA)BiI with a high degree of circularly polarized light (CPL) emission. Our 0D lead-free chiral perovskite exhibits an average degree of circular polarization (DOCP) of 19.8% at 78 K under linearly polarized laser excitation, and the maximum DOCP can reach 25.

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van der Waals heterostructures based on transition metal dichalcogenides (TMDs) provide a fascinating platform for exploring new physical phenomena and novel optoelectronic functionalities. Revealing the energy-dependence of photocarrier population dynamics in heterostructures is key for developing optoelectronic or valleytronic devices. Here, the broadband transient dynamics of interlayer excitation of a nearly-aligned WS/WSe heterostructure is investigated by using energy-dependent pump-probe spectroscopy at cryogenic temperatures.

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A total of 18% of global breast cancer (BC) deaths are attributed to BC in China, making it one of the five most common cancers there. There has been a steady rise in BC morbidity and mortality in women in the last few years and it is now a leading cancer among Chinese women. Conventional treatments for BC are currently effective but have several limitations and disadvantages, and Traditional Chinese medicine (TCM) plays a vital role in the overall process of cancer prevention and therapy.

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Introduction: The Meek micrografting technique used in STSG expansion is effective in achieving wide and rapid coverage of burn wounds. Certain growth factors have also been shown to modulate or mediate wound healing.

Objective: In this study, a combined treatment approach for severe burns involving the Meek micrografting technique, systemic application of rhGH, and topical application of rhEGF was evaluated.

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Article Synopsis
  • MicroRNAs (miRNAs) are crucial for chicken reproduction, particularly influencing the development and performance of granulosa cells in follicles.
  • A study used small RNA sequencing to identify differentially expressed miRNAs in various stages of follicle development, discovering a total of 405 unique miRNAs across several comparisons.
  • Key pathways associated with these miRNAs include MAPK, TGF-β, Wnt, Notch, and insulin signaling, indicating their significant role in regulating follicular development in chickens.
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Context: Gastric cancer (GC) is a significant contributor to global mortality and is recognized for its elevated prevalence and fatality rates. Nitric Oxide (NO) plays a role in multiple aspects of cancer metastasis and progression. CS-NO is a polysaccharide-based biomaterial with NO-releasing properties that shows promising therapeutic potential.

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Due to the short valley polarization time, it is hardly to separate opposite valley pseudospin of transition metal dichalcogenides (TMDs) for their practical applications in valleytronics. Coupling TMDs to unidirectional surface plasmon polariton (SPP) can overcome this obstacle. However, it is required to break the symmetry to induce the asymmetric coupling between valley exciton dipole and SPP to route valley exciton in previously proposed strategies.

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Although selective singlet and triplet interlayer exciton (IX) emission of transition metal dichalcogenides (TMD) heterostructures can be achieved by applying an electric or magnetic field, the device structure is complex and a low temperature is usually required. Here, we demonstrate a simple all-optical approach to selectively enhance the emission of singlet and triplet IX by selectively coupling singlet or triplet IX of a WS/WSe heterostructure to a SiO microsphere cavity. Angle-resolved photoluminescene reveals that the transition dipole of triplet IX is almost along the out-of-plane direction, while singlet IX only has 69% out-of-plane dipole moment contribution.

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Breast cancer (BC) is the most common type of cancer among females. Peroxisome proliferator-activated receptor gamma (PPARG) can regulate the production of adipocyte-related genes and has anti-inflammatory and anti-tumor effects. Our aim was to investigate PPARG expression, its possible prognostic value, and its effect on immune cell infiltration in BC, and explore the regulatory effects of natural drugs on PPARG to find new ways to treat BC.

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As the arid and semi-arid grassland with the most extensive distribution area in northern China, the carbon stored in Inner Mongolia (IM) grassland is highly susceptible to environmental changes. With the global warming and drastic climate changes, exploring the relationship between carbon pool changes and environmental changes and their spatiotemporal heterogeneity is necessary. This study estimates the carbon pool distribution of IM grassland during 2003-2020 by combining the measured below ground biomass (BGB) dataset, measured soil organic carbon (SOC) dataset, multi-source satellite remote sensing data products, and random forest regression modeling method.

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Objective: Given the immense stress faced by medical staff during the COVID-19 pandemic, this study aimed to evaluate the relationship between mindful attention awareness, fatigue, and perceived symptoms among frontline nurses who performed nucleic acid sample collection during the COVID-19 pandemic, to reduce their fatigue and help them cope with perceived uncomfortable symptoms.

Methods: A convenience sampling method was used to survey nurses who travelled to Hainan for nucleic acid sampling in August 2022 using an online (WeChat) questionnaire. A total of 514 frontline nurses who performed nucleic acid tests completed the questionnaire.

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Afforestation has been initiated in Northeast Asia to improve ecological status. The responses of the regional hydrological cycle to vegetation restoration remain insufficiently explored. This study uses a variety of satellite-derived vegetation variables and hydrological cycle components to scan the eco-hydrological regimes in the Three-North Region of China and Mongolia during the past four decades.

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Interlayer excitons (IXs) in type II van der Waals (vdW) heterostructures are equipped with an oriented permanent dipole moment and long lifetime and thus would allow promising applications in excitonic and optoelectronic devices. However, based on the widely studied heterostructures of transition-metal dichalcogenides (TMDs), IX emission is greatly influenced by the lattice mismatch and geometric misalignment between the constituent layers, increasing the complexity of the device fabrication. Here, we report on the robust momentum-indirect IX emission in TMD/two-dimensional (2D) perovskite vdW heterostructures, which were fabricated without considering the orientation arrangement or momentum mismatch.

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Objective: To analyze the rules of medication and principles of formulas for the treatment of coronavirus disease 2019 (COVID-19) using the traditional Chinese medicine inheritance support platform (V2.5).

Methods: The clinical data, including gender, age, clinical symptoms, frequency of traditional Chinese medicine medication and prescription information, of patients with COVID-19 and asymptomatic infection who were admitted to Hebei COVID-19 designated hospital supported by medical team of First Affiliated Hospital of Hebei University of Chinese Medicine from January to March 2021 were collected.

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