Background: Blunt chest injuries are the predominant cause of rib fractures, which frequently result in pulmonary complications. We hypothesized that different trauma mechanisms and fracture patterns are associated with pulmonary complications in elderly patients (≥65 years) with isolated rib fractures.
Methods: We retrospectively reviewed the data of patients with rib fractures recorded in the electronic medical record system of a trauma center from 2015 to 2019.
J Environ Sci (China)
August 2025
This study aims to identify the highly non-specific toxic by-products during ozonation of three cresols in wastewater. In ozonated effluents, biotoxicity increased along with increasing reaction time, followed by a gradual decrease. The peak biotoxicity for ozonated o-cresol (o-C), m-cresol (m-C), and p-cresol (p-C) was estimated to be 17.
View Article and Find Full Text PDFHalogen-substituted para-benzoquinones (p-BQs) are emerging disinfection byproducts known to induce oxidative damage both in vitro and in vivo. However, as ubiquitous oxidation byproducts, the in vivo toxicity and transport mechanism of non-halogenated p-BQs with similar structure of α, β-unsaturated ketones to halogenated p-BQs have not been thoroughly investigated. In this study, the effect of substituents on toxicity and transportation of 2-chloro-1,4-benzoquinone (CBQ) and 2-methyl-1,4-benzoquinone (MBQ) was systematically investigated.
View Article and Find Full Text PDFLiMnO, a significant cathode material for lithium-ion batteries, has garnered considerable attention due to its low cost and environmental friendliness. However, its widespread application is constrained by its rapid capacity degradation and short cycle life at elevated temperatures. To enhance the electrochemical performance of LiMnO, we employed a liquid-phase co-precipitation and calcination method to incorporate Cr into the LiMnO cathode material, successfully synthesizing a series of LiCrMnO (x = 0~0.
View Article and Find Full Text PDFNeglecting the time intervals between sampling and biological testing can lead to misinterpretation of the hazards associated with advanced oxidation processes when assessed through bioassays. This study investigates changes in the non-specific toxicity of ozonated aromatic compounds and analyzes the factors such as temperature and light exposure influencing these changes during sample storage. The findings reveal a significant decrease in biotoxicity of ozonated effluents, ranging from 41 % to 83 %, within the first four days of storage at 22 °C under natural light exposure.
View Article and Find Full Text PDFThe P2-NaMnO cathode material has long been constrained by phase transitions induced by the Jahn-Teller (J-T) effect during charge-discharge cycles, leading to suboptimal electrochemical performance. In this study, we employed a liquid phase co-precipitation method to incorporate Ti during the precursor MnO synthesis, followed by calcination to obtain NaTiMnO materials. We investigated the effects of Ti doping on the structure, morphology, Mn concentration, and Na diffusion coefficients of NaTiMnO.
View Article and Find Full Text PDFObjective: To explore the association between survival status and the number of resected lymph nodes in node-negative esophageal squamous cell carcinoma(ESCC) after surgical treatment.
Methods: This was a retrospective observational cohort study and data were obtained from the Surveillance, Epidemiology, and End Results program (SEER) and TaiZhou hospital in China. The data for subjects with negative lymph nodes and no distant metastasis (pN0M0) after post-operative pathology were screened.
The considerable grain growth occurring during the long-term high-temperature sintering of polycrystalline oxide fibers negatively affects their mechanical properties, which highlights the need for alternative sintering methods. Herein, open ultrafast high-temperature sintering (OUHS) in air, characterized by rapid heating/cooling (>10000 K min) and a short high-temperature holding time (<10 s), is used to produce 3 mol% yttria-stabilized zirconia continuous fibers with coherent boundaries forming robust connections between fine grains. The tensile strength of these fibers (2.
View Article and Find Full Text PDFThe application of nano-catalysts in improving the ozonation removal efficiency for refractory organic compounds has been extensively investigated. However, cost-effective nano-catalysts separation remains a challenge. In this study, membrane separation processes were employed to separate nano-MgO catalysts from an ozonation system.
View Article and Find Full Text PDFBackground: Traumatic tracheal rupture is a severe closed chest injury that often causes major respiratory and circulatory disturbances requiring emergency surgery. We have found that veno-venous extracorporeal membrane oxygenation (VV-ECMO) employs lung-protective ventilation strategies to facilitate lung rest, aiming to minimize the risk of ventilator-induced lung injury, while ensuring adequate oxygenation.
Case Description: We presented 3 critically ill patients who presented with traumatic bronchial rupture between 2019 and 2021, and underwent emergency thoracic surgery with the help of VV-ECMO.
Halobenzoquinones (HBQs) are a class of disinfection byproducts with high cytotoxicity and potential carcinogenicity, which have been widely detected in chlorination of drinking water and swimming pool water. However, to date, the formation of HBQs upon ozonation and the HBQ precursors have been overlooked. This study investigated the formation of chlorinated and dechlorinated HBQs from six dichlorophenol (DCP) isomers.
View Article and Find Full Text PDFTransl Lung Cancer Res
November 2023
Background: Chemoresistance is a significant factor contributing to tumor recurrence and treatment failure in non-small cell lung cancer (NSCLC). The phosphofructokinase, platelet (PFKP) is highly expressed in NSCLC and is associated with a poor prognosis. Exploring the molecular mechanism and identifying effective strategies to overcome chemoresistance will have important clinical significance in improving the diagnosis and treatment of NSCLC.
View Article and Find Full Text PDFBackground: The nature of the solid component of subsolid nodules (SSNs) can indicate tumor pathological invasiveness. However, preoperative solid component assessment still lacks a reference standard.
Methods: In this retrospective study, an AI algorithm was proposed for measuring the solid components ratio in SSNs, which was used to assess the diameter ratio (1D), area ratio (2D), and volume ratio (3D).
Recent advancements have introduced anisotropic structures, particularly 2D nanosheets, into aerogels, resulting in unique morphologies and exceptional properties that differ from those assembled by isotropic nanoparticles. However, exploration of the distinct porous networks and the resulting properties is limited. We focus on rare earth yttria (YO) aerogels as a case in point and demonstrate the synthesis of aerogels with nanosheet and nanoparticle assemblies using elaborative sol-gel chemistry.
View Article and Find Full Text PDFBackground: Invasive lung adenocarcinoma (LUAD) patients with the micropapillary (MPP) component tend to have extremely poor prognosis. To optimize clinical outcomes, a better understanding of specific concurrent gene alterations and their impact on the prognosis of patients with the MPP component is necessary.
Method: A total of 621 Chinese patients with surgically resected invasive LUAD who underwent genetic testing for lung cancer were enrolled in this retrospective study.
The toxicity assessment of transformation products (TPs) formed in oxidative water treatment is crucial but challenging because of their low concentration, structural diversity, and mixture complexity. Here, this study developed a novel redox-directed approach for identification of toxic TPs without the individual toxicity and concentration information. This approach based on sodium borohydride reduction comprised an integrated process of toxicological evaluation, fluorescence excitation-emission matrix characterization, high-resolution mass spectrometry detection, followed by ecological toxicity assessment of identified TPs.
View Article and Find Full Text PDFThe expression status of proinflammatory cytokines in high-altitude pulmonary arterial hypertension (PAH) has been well studied. However, the changes in interleukin (IL)-8 and tumor necrosis factor α (TNF-α) during the reversible changes in pulmonary vascular remodeling (PVR) in PAH after detaching from a hypobaric hypoxic environment have not been elucidated. This investigation elucidated a high-altitude PAH rat model.
View Article and Find Full Text PDFMicroorganisms have difficulty surviving and performing remediation functions in mixed systems with high concentrations of Pb and Cd. Biochar has the potential to assist microorganism remediation as an excellent adsorbent for heavy metals. In this study, pig manure biochar (PMB) was used to assist phosphorus solubilizing bacteria (PSB) to explore the mineralization protection and biofeedback mechanism of biochar on PSB under mixed stress of 1000 mg/L Pb and 500 mg/L Cd.
View Article and Find Full Text PDFThe inherent brittleness and hydrophilicity of ceramics pose a great challenge to designing a reliable structure that can resist mechanical loads and moisture in extreme conditions with high temperature and high humidity. Here, we report a two-phase hydrophobic silica-zirconia composite ceramic nanofiber membrane (H-ZSNFM) with exceptional mechanical robustness and high-temperature hydrophobic resistance. For the dual-phasic nanofibers, the amorphous silica blocked the connection of zirconia nanocrystals, and the lattice distortion was observed due to Si in the ZrO lattice.
View Article and Find Full Text PDFPrimary spontaneous pneumothorax (PSP) or pulmonary cyst is one of the manifestations of Birt-Hogg-Dubé syndrome, which is caused by pathogenic variants in FLCN gene. Genetic testing in patients with PSP identifies a certain number of missense or intronic variants. These variants are usually considered as variants of uncertain significance, whose functional interpretations pose a challenge in clinical genetics.
View Article and Find Full Text PDFBackground: Crigler-Najjar syndrome type 2 (CNS-II) is a rare genetic disease that is associated with a lack of uridine diphosphate-glucuronosyltransferase. Esophageal carcinoma is the sixth most common cause of cancer-related death worldwide, for which surgery is the most effective treatment. Reports on patients with both conditions requiring surgery are limited and The impact of hyperbilirubinemia caused by CNS-II on the perioperative period is unknown.
View Article and Find Full Text PDFIn this study, ozonation catalyst nano-MnO blended polyvinylidene fluoride (PVDF) membrane was fabricated via phase inversion method and applied to membrane bioreactors (MBR), and then coupled with in-situ ozonation to study the anti-biofouling performance and reveal its mechanism. Results showed that, compared with pristine PVDF membrane (MBR_M), 0.75 wt% and 1.
View Article and Find Full Text PDFBackground: Few studies have exclusively investigated the value of pathological complete response (pCR), in esophageal squamous cell carcinoma (ESCC) patients, although it is a clinically significant parameter to evaluate the impact of neoadjuvant chemoradiotherapy (nCRT) on treatment outcome after surgery. The aim of our study was to explore the relationship between pCR after nCRT and survival among patients with local ESCC.
Methods: All patients receiving nCRT followed by surgery in NEOCRTEC5010-trial (NCT01216527) were included.