[The effectiveness of rehabilitation measures using the drug Cortexin in children with neuropsychiatric pathology].

Objective: To evaluate the effectiveness of complex rehabilitation measures using the drug Cortexin in children with neuropsychiatric pathology during a one-year follow-up.

Material And Methods: A promising dynamic examination and treatment of 323 children with neuropsychiatric pathology from the age of 7 days to 1 year, age 3.2±1.

Intranasal Immunotherapy with M2 Macrophage Secretome Ameliorates Language Impairments and Autistic-like Behavior in Children.

: The intranasal delivery of various neurotropic substances is considered a new attractive therapeutic approach for treating neuropathologies associated with neuroinflammation and altered regeneration. Specific language impairment (SLI) that arises as a result of damage to the cortical speech zones during the developmental period is one of the most common problems in preschool children, and it is characterized by persistent difficulties in the acquisition, understanding, and use of language. This study's objective is to evaluate the efficacy and safety of intranasal immunotherapy using the M2 macrophage secretome as a rich source of immunoregulatory and neurotrophic factors for the treatment of severe language impairment in children.

Structural simplicity and complexity of compressed calcium: electronic origin.

A simple cubic structure with one atom in the unit cell found in compressed calcium is counterintuitive to the traditional view of a tendency towards densely packed structures with an increase in pressure. To understand this unusual transformation it is necessary to assume electron transfer from the outer core band to the valence band, and an increase of valence electron number for calcium from 2 to ∼ 3.5.

The fcc-bcc Bain path in In-Sn and related alloys at ambient and high pressure.

Experimental high-pressure structural studies on an In-Sn alloy containing 8 at.% Sn reveal an isostructural transition of a face-centered tetragonal phase at pressures above 15 GPa with a switch of the axial ratio from c/a>1 to c/a<1. Such tetragonal phases in binary alloys based on In and Sn are analyzed in relation to the Bain path, i.

Structural stability of the sigma phase FeCr under pressure up to 77 GPa.

A tetragonal σ phase of the equiatomic FeCr alloy was investigated by x-ray diffraction under pressure up to 77 GPa. The phase was found to be stable in the whole pressure range studied. The equation of state for the tetragonal phase was found to have a value of bulk modulus K(0) = 217(5) GPa and its pressure derivative was K(0)' = 5.

Hemogram and myelogram in progressing non-Hodgkin's lymphomas.

Parameters of hemogram and myelogram were studied in patients with aggressive and indolent non-Hodgkin's lymphomas: the relationships between the parameters recorded before treatment and during remission or progress 6 months after chemotherapy were studied by multifactorial analysis. The progress of indolent non-Hodgkin's lymphomas was associated with changes caused by tumor infiltration of the bone marrow; lymphocytosis in the myelogram or hemogram was associated with a relative decrease in the count of granulocytic hemopoietic stem cells. A sign associated with the absence of remission in aggressive non-Hodgkin's lymphomas was decreased level of hemoglobin and erythroid cells.

Erythropoiesis in patients with aggressive and indolent non-Hodgkin's lymphomas.

Parameters of the erythroid, granulocytic, and megakaryocytic hemopoietic stems were compared in 87 patients with aggressive and indolent non-Hodgkin's lymphomas before and 6 months after the start cytostatic therapy. Before chemotherapy anemia was detected in 46% patients with aggressive and 49% patients with indolent lymphomas. Hemoglobin content, peripheral blood erythrocyte count, and total count of erythroid cells in the bone marrow increased during chemotherapy in the indolent lymphoma group.

Structure solution in binary systems under high pressure: phase decomposition and phase synthesis.

There are binary systems (compounds) for which no structural solution can be found for a new high-pressure state by assuming a single phase. In accordance with Gibb's phase rule, an additional variable--composition--leads to an additional degree of freedom for a binary system (one more than in a one-component system). Although the bulk composition of a system may remain fixed, compositional variation between phases should be taken into account when considering phase transitions under pressure in binary compounds.