Effects of Er,Cr:YSGG Laser Surface Treatments and Composites with Different Viscosities on the Repair Bond Strength of CAD/CAM Resin Nanoceramic.

This study aims to evaluate the repair micro-shear bond strength of the CAD/CAM resin nanoceramic block treated using four different surface treatments and composite resins of different viscosities. For the current study, 96 samples with dimensions of 14 × 12 × 2 mm were obtained from a CAD/CAM resin nanoceramic block (Cerasmart) with a low-speed precision cutting saw under water cooling. The relevant samples were randomly divided into four groups according to the surface treatment processes: grinding with diamond bur, aluminum oxide airborne-particle abrasion, long-pulse laser, and short-pulse laser.

Redox-Responsive "Catch and Release" Cryogels: A Versatile Platform for Capture and Release of Proteins and Cells.

Macroporous cryogels are attractive scaffolds for biomedical applications, such as biomolecular immobilization, diagnostic sensing, and tissue engineering. In this study, thiol-reactive redox-responsive cryogels with a porous structure are prepared using photopolymerization of a pyridyl disulfide poly(ethylene glycol) methacrylate (PDS-PEG-MA) monomer. Reactive cryogels are produced using PDS-PEG-MA and hydrophilic poly(ethylene glycol) methyl ether methacrylate (PEGMEMA) monomers, along with a PEG-based cross-linker and photoinitiator.

Metal-Free Click-Chemistry: A Powerful Tool for Fabricating Hydrogels for Biomedical Applications.

Increasing interest in the utilization of hydrogels in various areas of biomedical sciences ranging from biosensing and drug delivery to tissue engineering has necessitated the synthesis of these materials using efficient and benign chemical transformations. In this regard, the advent of "" chemistry revolutionized the design of hydrogels and a range of efficient reactions was utilized to obtain hydrogels with increased control over their physicochemical properties. The ability to apply the "" chemistry paradigm to both synthetic and natural polymers as hydrogel precursors further expanded the utility of this chemistry in network formation.

The process of pollen transformation into bee bread: changes in bioactivity, bioaccessibility, and microbial dynamics.

Bee pollen and bee bread go hand in hand with health-promoting functional food consumption. Although many studies report high bioactivities of those products, the biotransformation of pollen into bee bread has not been fully understood. Limited findings are available about polyphenol bioaccessibility and microbiological interactions during the fermentation process.

Aesthetic rehabilitation for anterior teeth of dental fluorosis with direct composite veneers.

Intrinsic discoloration can be formed due to many reasons, and by clinical evaluation and history from the patient, the exact cause of the discoloration can be known and one of the reasons that can make the intrinsic discoloration is the high level of fluoride intake. Two siblings had come to the Department of Restorative Dentistry clinics; they had the same compliance which is severe dental fluorosis, caries, and malocclusion of their teeth. What is interesting and worrying is that some patients with severe dental fluorosis show higher levels of caries, which can be explained as the enamel becoming porous with severe fluorosis.

Plug-and-Play Biointerfaces: Harnessing Host-Guest Interactions for Fabrication of Functional Polymeric Coatings.

Polymeric surface coatings capable of effectively integrating desired functional molecules and ligands are attractive for fabricating bio-interfaces necessary for various applications. Herein, we report the design of a polymeric platform amenable to such modifications in a modular fashion through host-guest chemistry. Copolymers containing adamantane (Ada) moieties, diethylene glycol (DEG) units, and silyloxy groups to provide functionalization handles, anti-biofouling character, and surface attachment, respectively, were synthesized.

Effects of polishing procedures on optical parameters and surface roughness of composite resins with different viscosities.

The aims of this study were to evaluate the optical properties of flowable and injectable composites after polishing, such as translucency (translucency parameter [TP], TP), opalescence (OP-BW), chroma (C*ab), refractive index (RI), and change in surface roughness (Ra, Rz). Ninety disc-shaped samples were prepared from micro-hybrid, flowable, and injectable composites and divided into 3 groups according to the polishing systems (n=10). The RI was measured with an Abbe refractometer, and optical measurements were performed with a spectrophotometer.

"Clickable" Polymer Brush Interfaces: Tailoring Monovalent to Multivalent Ligand Display for Protein Immobilization and Sensing.

Facile and effective functionalization of the interface of polymer-coated surfaces allows one to dictate the interaction of the underlying material with the chemical and biological analytes in its environment. Herein, we outline a modular approach that would enable installing a variety of "clickable" handles onto the surface of polymer brushes, enabling facile conjugation of various ligands to obtain functional interfaces. To this end, hydrophilic anti-biofouling poly(ethylene glycol)-based polymer brushes are fabricated on glass-like silicon oxide surfaces using reversible addition-fragmentation chain transfer (RAFT) polymerization.

Gaussian process regression for ultrasound scanline interpolation.

In ultrasound imaging, interpolation is a key step in converting scanline data to brightness-mode (B-mode) images. Conventional methods, such as bilinear interpolation, do not fully capture the spatial dependence between data points, which leads to deviations from the underlying probability distribution at the interpolation points. We propose Gaussian process ( ) regression as an improved method for ultrasound scanline interpolation.

BODIPY and 2,3-Dihydrophthalazine-1,4-Dione Conjugates As Heavy Atom-Free Chemiluminogenic Photosensitizers.

We disclose an interesting concept for developing heavy atom-free chemiluminogenic photosensitizers. To accomplish this, conjugates and , which are composed of boron-dipyrromethene (BODIPY) and 2,3-dihydrophthalazine-1,4-dione units, are investigated. and are compared in terms of their photophysical properties, chemiluminescence responses, and singlet oxygen production.

Pregnancy and its outcomes in hemodialysis patients in Turkey.

Background/aim: This study aimed to investigate pregnancy frequency and evaluate the factors affecting live births in hemodialysis (HD) patients.

Materials And Methods: Female HD patients whose pregnancy was retrospectively reported between January 1, 2014, and December 31, 2019. The duration of HD, primary disease, whether the pregnancy resulted in abortion, stillbirth, or live birth, whether the HD duration was prolonged after diagnosing the pregnancy and whether it accompanied preeclampsia were recorded.

Intraoperative Temperature Monitoring with Zero Heat Flux Technology (3M SpotOn Sensor) in Comparison with Tympanic and Oesophageal Temperature and Hypotermia Risk Factors: An Observational Study.

Objective: Inadvertent hypothermia (body temperature below 35°C) is a common and avoidable challenge during surgery under anaesthesia. It is related to coagulation (clotting) disorders, an increase in blood loss, and a higher rate of wound infection. One of the methods for non-invasive monitoring of the core body temperature is the 3M SpotOn zero heat flux method.

Evaluation of gingival displacement methods in terms of periodontal health at crown restorations produced by digital scan: 1-year clinical follow-up.

The purpose of this clinical study was to compare the effects of the gingival displacement techniques of retraction cord, cordless paste system, and Er,Cr:YSGG laser troughing on the periodontal tissues around the crown restoration produced using a digital scan. This was analyzed by recording the probing depth (PD), plaque index, gingival index (GI), mobility, sensitivity, and bleeding on probing (BOP) index. This study included 60 mandibular 1 molars from 52 participants (20 males and 32 females) requiring crown restoration.

Automatically steering cardiac catheters in vivo with respiratory motion compensation.

A robotic system for automatically navigating ultrasound (US) imaging catheters can provide real-time intra-cardiac imaging for diagnosis and treatment while reducing the need for clinicians to perform manual catheter steering. Clinical deployment of such a system requires accurate navigation despite the presence of disturbances including cyclical physiological motions (e.g.

Multifunctional and Transformable 'Clickable' Hydrogel Coatings on Titanium Surfaces: From Protein Immobilization to Cellular Attachment.

Multifunctionalizable hydrogel coatings on titanium interfaces are useful in a wide range of biomedical applications utilizing titanium-based materials. In this study, furan-protected maleimide groups containing multi-clickable biocompatible hydrogel layers are fabricated on a titanium surface. Upon thermal treatment, the masked maleimide groups within the hydrogel are converted to thiol-reactive maleimide groups.

Ultrasound Imaging Characterization of Soft Tissue Dynamics of the Seated Human Body.

To characterize the dynamics of internal soft organs and external anatomical structures, this paper presents a system that combines medical ultrasound imaging with an optical tracker and a vertical exciter that imparts whole-body vibrations on seated subjects. The spatial and temporal accuracy of the system was validated using a phantom with calibrated internal structures, resulting in 0.224 mm maximum root-mean-square (r.

Wound Irrigation with Chlorhexidine Gluconate Reduces Surgical Site Infection in Pilonidal Disease: Single-Blind Prospective Study.

The aim of this study was to determine whether incision irrigation with chlorhexidine gluconate (CHG) reduces surgical site infections (SSIs) in pilonidal disease surgery. Between 2013 and 2018, patients who underwent wide excision with primary closure for pilonidal disease were enrolled in this prospective observational multi-institutional cohort. The incision was irrigated with either saline or 0.

Glucose-mediated protein glycation: Contribution of methanolic extract of Ceratonia siliqua L. in protection and in vitro potential inhibition of acetylcholinesterase.

Chronic hyperglycemia presents the major etiology of diabetes mellitus and related complications mainly Alzheimer's disease, via the protein glycation and toxic products generated. In the current study, we investigated the eventual protective effect of the methanolic extract of Ceratonia siliqua L. (CsME) against glucose-mediated glycation in serum bovine albumin.

The effect of pregabalin and ibuprofen combination for pain after third molar surgery.

Aim: The objective of this study was to compare the efficacy of different doses of pregabalin and intravenous ibuprofen with regard to pain management and analgesic consumption after third molar surgery.

Materials And Methods: Ninety patients who had been scheduled for third molar surgery were assigned to four different treatment groups. The inclusion criteria consisted of the presence of fully or partially bony retentive asymptomatic mandibular third molars.

Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces.

Objective: The aim of the present study was to compare the shear bond strength (SBS) of metal orthodontic brackets bonded to long-term water-aged and fresh porcelain and composite surfaces.

Methods: One porcelain (Vitadur Alpha (VA)) and three composite (Filtek Ultimate (FU), Tetric EvoCeram (TEC), and Gradia Direct Anterior (GDA)) materials were evaluated in the present study. First, 10 discs from each material were prepared and subjected to the aging procedure for 5 years.

Dendron-Polymer Conjugate Based Cross-Linked Micelles: A Robust and Versatile Nanosystem for Targeted Delivery.

Among various nanomedicine platforms, biodegradable polymeric micelles offer a viable approach to targeted cancer therapy. Herein, we report fabrication of core-cross-linked micelles using dendron-polymer conjugates as building blocks. Hydrophobic polyester dendrons containing peripheral alkene groups are conjugated to a hydrophilic poly(ethylene glycol) based copolymer bearing activated ester groups for appending an amine-containing peptide based targeting group, namely, cRGDfK.

Long-term follow-up of enamel color changes after treatment with fixed orthodontic appliances.

Introduction: The aim of this study was the long-term follow-up of enamel color changes observed in the middle third of buccal tooth surfaces after treatment with fixed orthodontic appliances.

Methods: The study included 120 maxillary central and lateral incisors and canines of 20 subjects who had fixed orthodontic treatment. The Spectro Shade Micro device (MHT, Verona, Italy) was used to evaluate the color changes of the teeth.

Diagnostic role of ultrasound elastography on lymph node metastases in patients with head and neck cancer.

Introduction: Ultrasonography is the easiest non-invasive method to diagnose lymph node metastases in patients with head and neck cancer. However, since CT scans are often preferred in the evaluation of primary tumours of these patients, information about lymphatic metastases may also available in these patients. Therefore, ultrasound is not routinely employed in the evaluation of these patients.

Multi-Functional Nanogels as Theranostic Platforms: Exploiting Reversible and Nonreversible Linkages for Targeting, Imaging, and Drug Delivery.

Nanogels that are amenable to facile multi-functionalization with imaging, therapeutic, and targeting agents are attractive theranostic platforms for addressing challenges in conventional diagnostics and therapy. In this work, reactive copolymers containing poly(ethylene glycol), maleimide, and pendant hydroxyl groups as side chains are used to construct nanogels by employing their thermoresponsive self-assembly in aqueous media. Subsequent cross-linking of these nanosized aggregates with dithiols using thiol-maleimide chemistry yields nanogels containing maleimide, thiol, and hydroxyl groups.