The association between the OPRM1 A118G polymorphism and addiction in a Turkish population.

Susceptibility to addiction has a complex genetic basis that includes genes associated with the action and metabolism of drugs of abuse. One important gene in that respect is OPRM1, which codes for the μ-opioid receptor and has an important role in mediating the rewarding effects of addiction substances. The aim of our study was to assess the prevalence of the OPRM1 A118G polymorphism (rs1799971) in Turkish population and to investigate its association with opioid and other substance addiction.

The development, validity, and reliability of the Addiction Profile Index (API).

Objective: The objective of this study was to develop a practical questionnaire for multidimensional assessment of problems associated with alcohol and substance abuse that would also be useful for treatment planning.

Materials And Methods: The Addiction Profile Index (API) is a self-report questionnaire consisting of 37 items and the following 5 subscales: characteristics of substance use; dependency diagnosis; the effects of subsance use on the user; craving; motivation to quit using substances. The study included 345 alcohol and/or substance abusers from 2 addiction treatment clinics and a prison addiction service.

Sexual problems in a sample of the Turkish psychiatric population.

Introduction: Sexual functioning has received little attention as an important aspect of patient care for those who have severe mental disorders.

Aim: The aim of this study is to compare sexual difficulties seen in Turkish psychiatric patients and healthy control subjects.

Methods: Study group consisted of outpatients in remission with schizophrenia (n = 84), bipolar affective disorders (n = 90), heroin addiction (n = 88), and healthy control group (n = 98).

Dissociative disorders among alcohol-dependent inpatients.

The aim of this study was to determine the prevalence of dissociative disorders among inpatients with alcohol dependency. The Dissociative Experiences Scale was used to screen 111 alcohol-dependent patients consecutively admitted to the inpatient unit of a dependency treatment center. Subgroups of 29 patients who scored 30.

Dissociative disorders among inpatients with drug or alcohol dependency.

Objective: To determine the prevalence of dissociative disorders among inpatients with alcohol or drug dependency.

Method: The Dissociative Experiences Scale was used to screen 215 consecutive inpatients admitted to the dependency treatment center of a large mental hospital over a 1-year period (March 1, 2003, to March 31, 2004). Patients who had scores of 30.