Yak IFNβ-3 enhances macrophage activity and attenuates Klebsiella pneumoniae infection.

Interferon-β (IFNβ) is an important member of the type I interferon family and plays key roles in antiviral response and treatment of autoimmune disease. However, the immunomodulation and antimicrobial potential of yak IFNβ3 protein are still unclear. In the current study, the 558 bp long cDNA sequence of the yak IFNβ3 gene was amplified and successfully expressed in a prokaryotic system.

Patient and Perioperative Factors Influencing the Functional Outcomes and Mortality in Elderly Hip Fractures.

This study aimed to evaluate the functional outcomes and mortality following hip fracture surgery in elderly patients, and to identify the associated risk factors. Between January 2016 and December 2017, 480 consecutive patients were finally included for data analyses. The Harris score and Barthel index were used to evaluate the hip function and ability to perform activities of daily living (ADL).