The mandibular first molar with three canals in the mesial root- a case report.

The dynamic concept of the root canal system, which describes a variable morphology of the multiple root canals which are inter-connected by anastomoses, has been established as the prevailing state in the mandibular molars. The aim of this case report was to describe the unusual root canal anatomy that was detected in the mandibular first molar during the routine endodontic treatment. The clinical and the radiographic examinations allowed the detection of the middle mesial root canal between the mesiobuccal and the mesiolingual root canals.

Effect of two different types of fibers on the fracture resistance of endodontically treated molars restored with composite resin.

Purpose: To compare the in vitro fracture resistance of endodontically treated molars with mesio-occluso-distal (MOD) cavities restored with two different types of fibers.

Materials And Methods: Sixty extracted human mandibular first molars were selected for the study and randomly assigned to six groups (n = 10). Group 1 served as the control.

Independent and confluent middle mesial root canals in mandibular first molars: a report of four cases.

Mandibular molars demonstrate considerable variations with respect to number of roots and root canals. The possibility of additional root canals should be considered even in teeth with a low frequency of abnormal root canal anatomy. This paper discusses the endodontic management of the rare anatomical complexity middle mesial canals in mandibular first molar and also serves to remind the clinicians that such anatomical variations should be taken into account during the endodontic treatment of the mandibular molars.

Pharmacokinetic drug interaction between gemfibrozil and sitagliptin in healthy Indian male volunteers.

Purpose: To study the impact of gemfibrozil co-administration on the pharmacokinetics of sitagliptin in healthy Indian male volunteers.

Methods: A randomized open label two-period crossover study involving 12 healthy Indian male volunteers was conducted at a single center. In each phase, the volunteers were administered sitagliptin as 100 mg tablets, either alone or co-administered with gemfibrozil as 600 mg tablets twice daily for 3 days.

Evaluation of the antibacterial and physical properties of glass ionomer cements containing chlorhexidine and cetrimide: an in-vitro study.

Background: Incorporation of antibacterial agents frequently results in changes in the physical properties of restorative materials.

Materials And Methods: This in-vitro study investigated the antibacterial and physical properties of Glass ionomer cement (GIC) with chlorhexidine and cetrimide, to determine the optimal concentration, for incorporation of these agents to obtain antibacterial GICs for use with the Atraumatic restorative treatment approach. This was assessed using the agar diffusion test.

Spiral CT diagnosis and endodontic management of an anatomically variant palatal root with two canals in a maxillary first molar.

This case report presents the endodontic management of an anatomically variant palatal root with 2 canals (Vertucci type II) in a maxillary first molar, which was confirmed with the help of spiral computed tomography (SCT). This serves to remind clinicians that such anatomic variations should be taken into account during the endodontic treatment of maxillary molars and highlights the invaluable aid of the SCT in accurate diagnosis and in negotiating the complex morphologic variations in root canals, thus enabling successful endodontic management.