Advancing Precision Medicine: Algebraic Topology and Differential Geometry in Radiology and Computational Pathology.

Precision medicine aims to provide personalized care based on individual patient characteristics, rather than guideline-directed therapies for groups of diseases or patient demographics. Images-both radiology- and pathology-derived-are a major source of information on presence, type, and status of disease. Exploring the mathematical relationship of pixels in medical imaging ("radiomics") and cellular-scale structures in digital pathology slides ("pathomics") offers powerful tools for extracting both qualitative and, increasingly, quantitative data.

A Review of Behavioral Tests to Evaluate Different Types of Anxiety and Anti-anxiety Effects.

Behavioral tests are very useful to understand the Neuro-psychotic disease and also helpful in finding the treatment of the particular disease. Nowadays various tests are available to evaluate the anxiolytics effect of a new entity or even for comparative studies with the standard drug. As per the ethics, a new compound or drug believes to have possible pharmacological effects should be tested on animals before tested on humans which have similar physiology than humans.

Perioperative management of critical right ventricular inflow obstruction from right atrial rhabdomyoma.

Rhabdomyoma is the most common cardiac tumor in infancy and commonly located in the ventricles causing outflow obstruction or arrhythmias. We report a rare pediatric (7 month old) case of a right atrial rhabdomyoma presenting with severe cyanosis and low cardiac output from significant tricuspid inflow obstruction with right to left shunt across a stretched patent foramen ovale. We present an emergency cardiac surgery for right atrial tumor resection, and the management of separating the patient with failing right ventricle from cardiopulmonary bypass using a Glenn shunt, since extracorporeal membrane oxygenation (ECMO) or nitric oxide was not available.

Kinetics of dissociation of tris-(2,2'-bipyridyl) iron(II) in water solubilized by Triton X-100 reverse micelles.

The dissociation of tris-(2,2'-bipyridyl) iron(II) ([Fe(bipy)3]2+) has been studied in the Triton X-100/hexanol/cyclohexane reverse micellar medium. The reaction obeys simple first-order kinetics with no evidence of autoinhibition. The first-order rate constant (k1) has been determined at different values of W ([H2O]/[Triton X-100]).