Personalized diagnosis of medulloblastoma subtypes across patients and model systems.

Molecular subtyping is instrumental towards selection of model systems for fundamental research in tumor pathogenesis, and clinical patient assessment. Medulloblastoma (MB) is a highly heterogeneous, malignant brain tumor that is the most common cause of cancer-related deaths in children. Current MB classification schemes require large sample sizes, and standard reference samples, for subtype predictions.