Publications by authors named "Dedy Ariwansa"
Background/aim: The leaves of Laurus nobilis have been used for culinary purposes for many years and have recently been shown to have beneficial effects on human health by altering microbiota composition. However, the effects of L. nobilis on the diversity of microbiomes in the oral cavity and gut remain unknown.
View Article and Find Full Text PDFBackground: Psychological stress is associated with changes in salivary flow and composition. However, studies to show the effect of psychological stress on the transcriptome of the salivary gland are limited. This study aims to perform a transcriptomic analysis of the submandibular gland under psychological stress using a chronic restraint stress model of rats.
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- Amitriptyline, a tricyclic antidepressant used for chronic orofacial pain, may alter oral microflora and innate immunity, though its specific effects were previously unclear.
- In a study with Sprague-Dawley rats, amitriptyline was administered for two weeks, during which researchers analyzed changes in the oral microbiome and antimicrobial peptide levels through DNA sequencing and mRNA evaluation.
- Results revealed significant shifts in oral bacteria composition and increased antimicrobial peptide expression in the amitriptyline group, indicating that this medication may influence oral health and immunity.
Introduction: Apart from the epithelial cell rests of Malassez (ERMs), dental pulp (DP) contains the same types of mesenchymal cells as the periodontal ligament (PDL). ERMs may affect the characteristics of the mesenchymal cells in the PDL. The aim of this study was to examine whether DP cells cultured with ERMs and human umbilical vein endothelial cells (HUVECs) could transform into PDL-like cells.
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