An antitumorigenic role for the IL-33 receptor, ST2L, in colon cancer.

Background: Despite the importance of inflammation in cancer, the role of the cytokine IL-33, and its receptor ST2, in colon cancer is unclear. The aim of this study was to investigate the role of IL-33, and its receptor isoforms (ST2 and ST2L), in colon cancer.

Methods: Serum levels of IL-33 and sST2 were determined with ELISA.