Protective effects of on hepatoxicity and nephrotoxicity induced by carbon tetrachloride in rats.

The aim of this study was to assess the protective effects of oral and topical treatment with (BP) against carbon tetrachloride (CCl) induced toxicity. Fifty-six rats were divided into seven groups: A: CCl only; B: CCl+oral BP; C: CCl and topical BP; D: CCl+oral and topical BP; E: oral BP only; F: negative control; and G: positive control (cyclophosphamide). The animals were treated for 10 weeks.