Publications by authors named "Deche Sanga"
Article Synopsis
- The study examines TB/HIV co-infection trends and treatment outcomes in Kenya from 2012 to 2020, focusing on a large population of TB patients.
- A significant decline in the proportion of HIV-infected TB patients from 32% in 2012 to 24% in 2020 was observed, along with high treatment adherence rates for TB and anti-retroviral therapy.
- However, HIV-infected individuals faced lower odds of completing TB treatment and had a higher risk of mortality and defaulting on treatment compared to those who were HIV-negative.
Background: Tuberculosis (TB) is one of the leading causes of deaths in Africa, monitoring its treatment outcome is essential to evaluate treatment effectiveness. The study aimed to evaluate proportion of poor TB treatment outcomes (PTO) and its determinants during six-months of treatment at Kilifi County, Kenya.
Methods: We conducted a retrospective analysis of data from the TB surveillance system (TIBU) in Kilifi County, Kenya from 2012 to 2019.
Article Synopsis
- The World Health Organization's criteria allow for diagnosing TB based on clinical signs without lab confirmation, especially in resource-limited settings like Kenya.
- A study evaluated treatment outcomes for TB patients in Kenya, comparing those diagnosed clinically versus those with bacteriological confirmation, analyzing data from 2012 to 2018.
- Among 12,856 patients, results showed similar treatment success rates (82% for clinical vs 83% for bacteriological diagnoses), but higher mortality in clinically diagnosed patients (9.9%).
Article Synopsis
- In 2016, TB caused 1.7 million deaths globally, prompting a study in Kilifi County, Kenya, to analyze all-cause mortality rates and associated features among TB patients from 2012 to 2016.
- The analysis involved 10,717 patients, revealing a 5.5% mortality rate, which increased from 7.8 to 17.7 deaths per 100 person-years over the study period, with most deaths occurring within the first three months post-treatment initiation.
- Significant risk factors for mortality included age, gender, type of TB, malnutrition, HIV status, and the year of diagnosis, highlighting the need for further research into the underlying causes of increasing mortality rates among TB patients.