Personal Resources and Expectations and Health Behaviors Among Solid Organ Transplant Recipients-A Multicenter Study.

Background: The long-term success of organ transplantation (Tx) depends on the transplant recipient's ability to self-manage symptoms, treatment, lifestyle changes, and psychosocial consequences. Health behavior (HB) determinants include personality traits such as optimism, self-efficacy, and health locus of control.

Purpose: Assessing the relationship between personal resources and expectations and health behaviors of organ transplant recipients.

Polish validation of the Transplant Effects Questionnaire.

Introduction: The Transplant Effects Questionnaire (TxEQ) assesses specific recipients' reactions to receiving a transplanted organ, including worry about the transplant, Guilt regarding the donor, disclosure of having undergone transplantation, adherence to medical treatment, and responsibility to the donor, family, or medical staff. Poland has no standardized tool for evaluating the emotional reaction to transplantation. The study aimed to assess the basic psychometric properties, such as the reliability and validity of the Polish translation of TxEQ-PL.

Health Locus of Control and Health Behaviors in Organ Transplant Recipients: A Multicenter Study.

Background: Adherence to health behaviors and to immunosuppressant medications are variables among heart transplant recipients with potential life-threatening outcomes. It is understood that patients with psychosocial barriers are at increased risk of poor outcomes due to various factors. Health locus of control includes any activity that can be done to prevent health problems.

Analysis of the health situation of women referring to breast cancer screening in Poland.

Purpose: To analyze the health situation of women referring to breast cancer screening.

Methods: The study was conducted at "Certus" Medical Center in Myslenice (Malopolska Province). A total of 808 women aged 51-69 years were enrolled.

Level of Life Quality in Heart and Kidney Transplant Recipients: A Multicenter Study.

Objective: The main objective of the researchers was to determine the level of life quality among heart and kidney transplant recipients depending on the time and type of the transplant.

Methods: The study was conducted using standardized questionnaires: the 36-Item Short-Form Health Survey, Life Orientation Test-Revised, and Hospital Anxiety and Depression Scale. The study included 146 recipients (109 heart transplant recipients and 37 kidney transplant recipients) from 1 to 26 years after the transplantation surgery (mean 9 years).

Continuous professional development of nurses and ICNP introduction in Poland.

Objectives: The aim of the study was to explore Polish nurses' readiness to use the International Classification for Nursing Practice (ICNP) as part of continuous professional development and life-long learning.

Material And Methods: The study included 772 nurses, divided into 2 study groups. The first group comprised those who had participated in a course enhancing the knowledge and improving skills in the use of ICNP terminology (N = 457).

The Quality of Life as a Predictor of Social Support for Multiple Sclerosis Patients and Caregivers.

Background: Coping with a diagnosis of multiple sclerosis (MS) is challenging. MS is one of the most common causes of nontraumatic disability in young adults, and patients may need assistance with daily life activities. This article explores the relation between quality of life (QOL) and the perceived available social support among patients with MS and their families.

The mediational effect of coherence on the relationship between mental load and job burnout among oncology nurses.

Aims: The purpose of this study was to determine the mediational effect of coherence on the relationship between mental load and job burnout among oncology nurses.

Background: Working stress and strain cause high mental load and can lead to job burnout among oncology nurses. Sense of coherence protects against the negative consequences of occupational mental load and may prevent professional burnout.

Evaluation of quality of life predictors in adolescents and young adults with cystic fibrosis.

Background: Cystic fibrosis (CF) is a chronic disease that has an impact on Health-Related Quality of Life (HRQoL).

Objectives: To identify demographic and clinical factors associated with HRQoL in adolescents and young adults with CF.

Methods: The sample comprised adolescent and young adult patients with CF.

Knowledge, compliance with good clinical practices and barriers to effective control of postoperative pain among nurses from hospitals with and without a "Hospital without Pain" certificate.

Aims And Objectives: (i) To compare knowledge and compliance with good clinical practices regarding control of postoperative pain among nurses employed at hospitals with and without a "Hospital without Pain" certificate, (ii) to identify the determinants of nurses' knowledge and (iii) to define barriers to effective control of postoperative pain.

Background: Only a slight improvement in postoperative pain control has been observed recently, if any. Implementation of good clinical practices in the control of postoperative pain requires involvement of nurses.

Perceived social support and the sense of coherence in patient-caregiver dyad versus acceptance of illness in cancer patients.

Background: Acceptance of illness is a significant determinant of further coping with a disease. Development of illness acceptance may be associated with the sense of coherence and perception of social support. Cancer is an example of a crisis situation, which affects both the patient and his/her close relatives.

Sense of Coherence vs. Mental Load in Nurses Working at a Chemotherapy Ward.

Objective: The aim of this study was to analyze the relationship between the sense of coherence and the level of mental load among nurses working at a chemotherapy ward.

Methods: The study, conducted in 2013, included 164 nurses working at inpatient chemotherapy wards in Krakow, Poznan, Kielce, and Gliwice (Poland). The mean age of the study participants was 43.

Factors related to changes in the quality of life among Polish adolescents and adults with cystic fibrosis over a 1-year period.

Background: The aim of this study was to determine the effects of clinical factors, physical activity, and sociodemographic variables on 1-year changes in health-related quality of life (HRQoL) in Polish adolescents and adults with cystic fibrosis (CF).

Method: The study included 67 subjects with CF (mean age 21.1±5.

Quality of life in patients with cystic fibrosis depending on the severity of the disease and method of its treatment.

Introduction: Quality of life is a measure not only of disease severity and its functional impact (physical, psychological, and social functioning) but also the efficacy of novel therapies. The aim of this study was to analyze the quality of life in cystic fibrosis patients depending on the severity of the disease and methods of its treatment.

Material/methods: The study included groups of cystic fibrosis patients: 1) after lung transplantation, 2) requiring chronic oxygen therapy, and 3) in stable clinical status.

Health-related quality of life of patients with cystic fibrosis assessed by the SF-36 questionnaire.

Introduction: Cystic fibrosis (CF) is a genetic disorder, which is most common among Caucasians. There are about 100,000 people suffering from this disorder in the world, including 25 000 in Europe. Although the first mention of cystic fibrosis is thought to have occurred in 1595, recognition of the entire clinical spectrum of CF and the resultant development of contemporary knowledge occurred in the 20th century.

[Psychometric properties assessment of the Meister questionnaire (Polish version) used in evaluating mental load among nurses].

Background: The objective of this study was to assess psychometric properties of the Polish version of the Meister questionnaire for subjective assessment of work-related mental load among nurses.

Material And Methods: A group of 211 nurses (mean age, 43.1 +/- 7.

Patient's perception of the meaning of life in cystic fibrosis--its evaluation with respect to the stage of the disease and treatment.

Introduction: Cystic fibrosis (CF) is related to physical and mental barriers. The objective of this work was to evaluate and compare patients' perception of sense of life in cystic fibrosis in different stages of their disease and therapeutic methods.

Material/methods: The study group included 45 patients divided into 3 subgroups: after lung transplantation, waiting for lung transplantation and with cystic fibrosis in stable condition.

[The perception of the purpose and sense of life among cystic fibrosis patients after lung transplantation].

Patients with cystic fibrosis keep struggling with their disease despite the improvement of their lung function after lung transplantation. Also, they often have to define and verify their purpose and sense of life once again. Therefore, an attempt to search answers to the questions: what health is, what one is expecting form his/her life, and what value this life after lung transplantation has for him/her; seems significant.

[Validation of Polish version of CFQoL in patients with cystic fibrosis].

Unlabelled: Cystic Fibrosis Quality of Life Questionnaire (CFQoL), is a specific measurement tool of quality of life in adolescents and adults with cystic fibrosis, fully verified in English-speaking countries. However, introduction of new language version requires validation process. The aim of this study was to validate Polish version of CFQoL questionnaire.

[CFQoL questionnaire as an assessment tool of quality of life in patients with cystic fibrosis].

The number of studies assessing quality of life, QOL, in patients with cystic fibrosis is quite small in world's and Polish literature, when compared with explosion of research concerning that topic in other disorders of the respiratory system. It is due to the fact that usage of general questionnaires or measures specific for other respiratory diseases turns out to be insufficient in the case of cystic fibrosis. Therefore, studies aimed at development and utilization of specific quality of life measures in cystic fibrosis are recommended.

Anti-apoptotic function of gelsolin in fas antibody-induced liver failure in vivo.

Apoptosis is a key mechanism underlying fulminant hepatic failure. The role of gelsolin in such apoptotic pathways is not well understood because both pro-apoptotic and anti-apoptotic effects have been reported in vitro, depending on the cell type and in vitro expression model used. Therefore, we studied an in vivo model of hepatic failure by analyzing expression of gelsolin; intrahepatic activation of caspase-3, -8, and -9; and the extent of apoptosis in gelsolin knockout (gsn(-/-)) versus wild-type mice (gsn(+/+)) after exposure to stimulatory Fas antibody Jo-2.

Low and high molecular weight poly(L-lysine)s/poly(L-lysine)-DNA complexes initiate mitochondrial-mediated apoptosis differently.

Poly(L-lysine)s, PLLs, are commonly used for DNA compaction and cell transfection. We report that, although PLLs of low (2.9 kDa), L-PLL, and high (27.

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy.

Poly(ethylenimine) (PEI) is a cationic macromolecule commonly used in gene transfer/therapy protocols with high transfection efficiency both in vitro and in vivo. PEI is also cytotoxic, but the molecular basis of its cytotoxicity is poorly understood. Here, we have demonstrated that branched (25 kDa) and linear (750 kDa) PEI can both induce membrane damage and initiate apoptosis in three clinically relevant human cell lines (Jurkat T cells, umbilical vein endothelial cells, and THLE3 hepatocyte-like cells).

Antidiabetic sulphonylureas activate mitochondrial permeability transition in rat skeletal muscle.

Antidiabetic sulphonylureas can bind to various intracellular organelles including mitochondria. The aim of this study was to monitor the influence of antidiabetic sulphonylureas on membrane permeability in mitochondria isolated from rat skeletal muscle. The effects of glibenclamide (and other sulphonylurea derivatives) on mitochondrial function were studied by measuring mitochondrial swelling, mitochondrial membrane potential, respiration rate and Ca2+ transport into mitochondria.