Cognitive outcome at 5 years in very premature children without severe early cerebral abnormalities. Relationships with EEG at 6 weeks after birth.

Aims Of The Study: This prospective study aimed to analyze the relationship between EEG at 6 weeks after birth and cognitive outcome at the age of 5 in children born very preterm who did not present with severe neonatal cerebral abnormalities.

Patients And Methods: EEGs were recorded at 6 weeks of age in infants born <29 weeks of gestation or weighing <1000 g at birth. At 5 years, study participants underwent a neurological assessment and cognitive evaluation with the Kaufman Assessment Battery for Children (K-ABC).

EEG at 6 weeks of life in very premature neonates.

Objective: To analyze EEG findings, especially chronic-stage EEG abnormalities, i.e., dysmature and disorganized patterns, during the late neonatal period in very premature infants without severe early cranial ultrasound and/or EEG abnormalities.

[Congenital methemoglobinemia: a rare case of cyanosis in the newborn].

We report the case of a newborn presenting a cyanosis after the birth with a good general state. Congenital methemoglobinemia is a rare disease which is characterized by a brutal appearance, in early infancy, of a bluish skin color not regressing with oxygen inspiration, and by a good general state. It is due to the recessive autosomal NADH-cytochrome b5 reductase (EC.

Serum opioid activity after physical exercise in rats.

In order to study the effect of exercise on the total serum opioid activity, female rats were trained for 3 weeks on a motor-driven treadmill and the experiment was ended by a final strenuous run until exhaustion. The serum samples were taken immediately after the final run and were analyzed by radioreceptor assay. Despite considerable interindividual variations, serum opioid activity, expressed in met-enkephalin equivalents (ME eq +/- S.

[Carbamazepine-fluvoxamine interaction. Consequences for the carbamazepine plasma level].

The current practices concerning psychotropic drugs use plasma levels for the therapeutic adaptation and for the prevention of overdose and side effects. We observed, among two patients treated with constant dosages of carbamazepine (CBZ), that the addition of fluvoxamine (FLV) has increased significantly plasma levels of CBZ. The first patient, suffering of an affective bipolar trouble (ICD-10), was hospitalized for major depression.

Neonatal seizures--recent aspects.

This study reports the neonatal aspects and prognosis of seizures observed in 71 neonates from 1.3. 1980 to 30.

[Premature infants delivered by cesarean section before the 32d week of pregnancy].

Sixty-one premature babies delivered by caesarean section (Group C) before the 32nd week of amenorrhoea were compared with 83 control babies (Group T) born by vaginal delivery. The mortality was comparable: 28 and 32.5%, which is statistically more significant in children born before the 28th week of pregnancy (100 and 66% respectively) and weighing less than 1000 g (53 and 57%).

[Partial trisomy of chromosome 3 resulting from paternal translocation].

The authors report a case of a 3 year-old patient presenting with partial trisomy of the short arm of chromosome 3. According to 21 previously published cases, the main features characterizing this chromosomal abnormality which is mainly observed in males are: cranio-facial dysmorphy, cardiac and genito-urinary malformations, psychomotor retardation. Cytogenetic studies always show an inherited balanced translocation allowing a possible prenatal diagnosis.

[Acute fetal distress and mental retardation. A prospective study (author's transl)].

A prospective study of neonatal status with a follow-up of 4 to 7 years, was performed in 74 full-term newborns with acute fetal distress (AFD). They were born between 0.1.

[Diagnosis and outcome of cerebral distress in newborn infants who presented signs of fetal hypoxia. Prospective study].

The prospective study covered 60 full-term newborns, who presented exclusively signs of acute fetal distress. It had two major aims: --the analysis of the clinical and EEG symptomatologies, allowing the assessment of the cerebral damage in the neonatal period; --the evaluation as to whether the post-asphyxia cerebral damage may remain undiagnosed in the neonatal period, sequellae revealing it secondarily. Clinical and EEG supervision was undertaken during the first week; it was continued till 3 years of age in 45 of the 56 survivors.