Multiplex viral polymerase chain reaction testing using the FilmArray device compared with direct fluorescent antibody testing.

Advances in fluidics, electronics, and instrument design have enabled automation of complex molecular assays. The FilmArray Respiratory Panel (RP) is one such assay; it allows for rapid detection of multiple viral and bacterial respiratory targets via nested polymerase chain reaction (PCR), with all components contained within a single pouch. We performed a detailed comparison of workflow between the FilmArray RP and direct fluorescent antibody (DFA) staining.

The effect of medicated chewing gums on oral health in frail older people: a 1-year clinical trial.

Objectives: To determine the effects of a medicated chewing gum on the oral health of frail older people.

Design: A controlled, double-blind trial using three groups based on random allocation of residential homes.

Setting: Sixteen residential homes in West Hertfordshire, England.