Publications by authors named "Debra M Lundquist"
Purpose: Early-phase clinical trials (EP-CTs) are designed to determine optimal dosing, tolerability, and preliminary activity of novel cancer therapeutics. Little is known about the time that patients spend interacting with the health care system (eg, time toxicity) while participating in these studies.
Methods: We retrospectively reviewed the electronic health records of consecutive patients enrolled in EP-CTs from 2017 to 2019 to obtain baseline characteristics and number of health care-associated days, defined as all inpatient and outpatient visits while on trial.
Purpose: To identify early-phase clinical trial (EP-CT) participants at risk for experiencing worse clinical outcomes and describe receipt of supportive care services.
Methods: A retrospective review of the electronic health records of consecutive patients enrolled in EP-CTs from 2017 to 2019 examined baseline characteristics, clinical outcomes, and receipt of supportive care services. The validated Royal Marsden Hospital (RMH) prognosis score was calculated using data at the time of EP-CT enrollment (scores range from 0 to 3; scores ≥ 2 indicate poor prognosis).
Purpose: To conduct a detailed content analysis of the theme "I'm still Mom" as described by young women living with advanced breast cancer.
Participants & Setting: 12 young adult women living with advanced breast cancer were recruited from across the United States.
Methodologic Approach: van Manen's hermeneutic phenomenologic method was used to analyze qualitative data from interviews and establish subthemes.
Cutaneous metastases (CMs) signal the spread of a primary tumor to the skin and dermis, particularly in patients with melanoma or with breast, lung, or gastrointestinal cancers. Although these lesions may present as superficial and painless, some CMs may lead to ulceration, drainage, and discomfort, causing distress to patients. Oncology nurses require knowledge about the clinical presentation of CMs, including incidence, pathophysiology, diagnostic evaluation, and complex symptomatology, as well as standard treatment and care for patients.
View Article and Find Full Text PDFProblem Identification: Knowledge about the experiences of adolescents and young adults (AYAs) living with advanced cancer may be limited. This review was conducted to examine the literature concerning this subject.
Literature Search: A comprehensive search was conducted using CINAHL®, the Cochrane Library of Systematic Reviews, Embase®, the Joanna Briggs Institute (JBI), and PubMed®.
Purpose: To describe and interpret the lived experiences of young women with advanced breast cancer.
Participants & Setting: 12 women, aged 25-39 years with advanced breast cancer, were recruited from private Facebook groups for women with breast cancer.
Methodologic Approach: Van Manen's hermeneutic phenomenologic method was used.