Publications by authors named "Debra Kurtz"
Article Synopsis
- Solute carrier family 4 (SLC4) transporters play a key role in transporting bicarbonate, chloride, and carbon dioxide, which are vital for regulating pH and maintaining ion balance in cells.
- Recent studies on human anion exchanger 1 (hAE1) and human electrogenic sodium bicarbonate cotransporter 1 (hNBCe1) revealed their similar three-dimensional structures but differing transport modes—Cl/HCO exchange vs. Na-CO symport.
- Using techniques like ligand competitive saturation mapping and molecular dynamics, researchers identified important substrate binding sites in both transporters, with specific mutations affecting their transport function, offering insights that could aid drug development for related diseases.
The integration of information technology into daily patient care potentially provides a means to standardize care and enable continuous quality improvement through improved communication among care teams. A 2-month observational study was conducted on 38 residents with pressure ulcers at a 51-bed skilled nursing facility to rate the Ease of Use and Wound Management Effectiveness of a point-of-care electronic wound documentation system. Nine nurses evaluated the use of handheld "smart phone" devices equipped with a digital camera to document pressure ulcer assessment and treatment at point of care.
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