Changes in hormones and biomarkers in polycystic ovarian syndrome treated with gastric bypass.

Background: Small retrospective studies have demonstrated reduction in weight and co-morbid hirsutism and diabetes in women with polycystic ovary syndrome (PCOS) treated with Roux-en-Y gastric bypass. The objective of this study was to prospectively determine clinical improvements in obese women with PCOS treated with gastric bypass and identify postoperative biomarker changes.

Methods: Data were collected on obese women with PCOS undergoing Roux-en-Y gastric bypass over 1 year.