Publications by authors named "Deborah R Gersony"
Background: Our purpose was to assess the prevalence and clinical implications of left ventricular (LV) and right ventricular (RV) diastolic dysfunction (DD) in patients with repaired tetralogy of Fallot (TOF).
Methods: Adults with repaired TOF at 11 North American congenital heart disease centres were included. Of 556 patients analyzed, 325 had sufficient Doppler data to evaluate for LV DD, defined as mitral lateral e' < 10 cm/s and E/e' ratio > 9.
Background: Although aortic root pathology has been described in patients with tetralogy of Fallot, the scope of the problem remains poorly defined. We sought to determine the prevalence and predictors of aortic root dilatation in adults with repaired tetralogy of Fallot.
Methods And Results: A multicenter cross-sectional study was conducted with standardized reassessment of echocardiographic parameters in 474 adults (≥18 years) with surgically repaired tetralogy of Fallot or pulmonary atresia with ventricular septal defect.
Article Synopsis
- *The study revealed that 14.4% had mildly decreased and 6.3% had moderately to severely decreased left ventricular (LV) function.
- *Factors like male gender, longer duration of shunt before repair, history of arrhythmia, and right ventricular (RV) dysfunction were linked to greater LV dysfunction severity.
Background: Cardiopulmonary exercise testing is often used to evaluate exercise capacity in adults with congenital heart disease including women who are considering pregnancy. The relationship between cardiopulmonary exercise testing parameters and pregnancy outcome has not been defined.
Methods And Results: We conducted a multicenter retrospective observational study of women with congenital heart disease who had undergone cardiopulmonary exercise testing within 2 years of pregnancy or during the first trimester.
Article Synopsis
- The study examined arrhythmias in adults with tetralogy of Fallot, finding that 43.3% experienced sustained arrhythmias or interventions.
- Prevalence rates for specific arrhythmias included 20.1% for atrial tachyarrhythmias and 14.6% for ventricular arrhythmias, with older age, cardiac surgeries, and heart structure changes being significant risk factors.
- Atrial fibrillation and ventricular arrhythmias were found to increase notably after age 45, highlighting a considerable arrhythmia burden tied more to left-sided heart conditions than to right-sided ones.
Objectives: The objective of this study was to document the prevalence of chronic venous insufficiency (CVI) and its associated factors in adults with Fontan physiology.
Background: As the population of adults with complex congenital heart disease and Fontan physiology increases, so does the occurrence of highly morbid and mortal outcomes, including heart failure and thromboembolism. The presence of abnormal peripheral hemodynamic conditions in this population and their potential contribution to adverse outcomes is not well known.
Objective: To assess the effect of beta-blockade therapy on clinical outcome in patients with Marfan's syndrome.
Background: Despite the lack of definitive evidence to support its efficacy, beta-blocker therapy is widely used prophylactically in patients with Marfan's syndrome.
Methods: A meta-analysis was instituted, which included studies identified by a systematic review of MEDLINE of peer-reviewed publications and by abstracts from annual scientific meeting.
Background: The Ross procedure is commonly used to treat aortic valve disease in pediatric and adult patients. For infants, data are limited regarding survival, reintervention, autograft growth, and function.
Methods And Results: The Ross procedure was performed in 27 infants <18 months of age (median age 5.
Aneurysm of the membranous ventricular septum (AMS) is a congenital cardiac anomaly often associated with ventricular septal defect. This aneurysm usually pouches into the right side of the heart and remains intracardiac. An AMS that extends outside of the heart is rare.
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