Publications by authors named "Deborah Preiti"
Besides recent advances in neonatal care, preterm newborns still develop sex-biased behavioral alterations. Preterms fail to receive placental insulin-like growth factor-1 (IGF-1), a major fetal growth hormone in utero, and low IGF-1 serum levels correlate with preterm poor neurodevelopmental outcomes. Here, we mimicked IGF-1 deficiency of preterm newborns in mice by perinatal administration of an IGF-1 receptor antagonist.
View Article and Find Full Text PDFArticle Synopsis
- Extra-uterine growth restriction (EUGR) is linked to poor development outcomes in very-low-birth-weight neonates, with a study of 288 patients examining various factors influencing growth and development.
- The research found that a higher weight z-score at 6 months positively impacts overall developmental quotient (DQ) at 2 years, while EUGR at that age correlates with poorer performance across multiple developmental areas.
- The findings highlight the importance of improved post-discharge nutrition and family education to support better growth and development in vulnerable infants.
Background: During the last decades, severe brain lesions affecting very low birth weight (<1500 gr, VLBW) infants were gradually substituted by milder lesions with debatable prognoses.
Objective: The objective of this study is to define type, frequency and 3 years of neurodevelopmental outcome of prematurity-related brain lesions in a modern cohort of VLBW infants.
Methods: VLBW infants admitted to our NICU in 5 years period with brain MRI at term-equivalent age were included.
The pandemic seen through the eyes of the youngest people: evaluating psychological impact of the early COVID-19 related confinement on children and adolescents through the analysis of drawings and of an e-survey on their parents.
Minerva Pediatr (Torino)
July 2022
Background: COVID-19 is having a significant impact on long term children' and adolescents' psychological health. We aimed to evaluate the direct early psychological and behavioural signs related to the COVID-19 pandemic outbreak and related confinement on children and adolescents.
Methods: Children and adolescents' drawings were collected for a limited time window (16th March-10th April 2020) and analyzed.
The COVID-19 pandemic has changed individuals' lifestyles to a great extent, particularly in Italy. Although many concerns about it have been highlighted, its impact on children and adolescents has scarcely been examined. The purpose of this study was to explore behavioral consequences and coping strategies related to the pandemic among families in Italy, by focusing on developmental ages from the caregivers' perspective, 3 weeks into quarantine.
View Article and Find Full Text PDFBackground: Post-haemorrhagic ventricular dilatation (PHVD) still represents an important cause of brain injury in premature infants. Intervention for PHVD is recommended once Ventricular Index (VI) crosses the 97th percentile + 4 mm line according to Levene.
Objectives: We aimed to compare PHVD severity, timing of intervention, and outcome between outborn infants transferred to a level IV NICU in order to be treated for PHVD and a control population of inborn infants.