Publications by authors named "Deborah Makanjuola"

To date, loop diuretics are the mainstay treatment for decongestion in patients with acute decompensated heart failure (HF). In clinical practice, loop diuretics have also been utilized for patients with chronic HF with reduced and preserved ejection fractions. There is a paucity of quality evidence of the effect of loop diuretics use and dosing on clinical outcomes in HF patients beyond symptomatic relief.

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Article Synopsis
  • The United States still faces high infant mortality rates, ranking poorly among developed countries despite significant healthcare spending improvements.
  • A study examined neonatal deaths using data from 2015 to 2019, identifying key maternal risk factors such as age, pregnancy complications, and prenatal care.
  • Key findings revealed that certain interventions like labor induction and augmentation reduced neonatal mortality, while older maternal age and lack of prenatal care increased risks; these insights could help improve neonatal health outcomes.
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Introduction Gestational diabetes mellitus (GDM) is a major contributor to adverse pregnancy outcomes both in the United States and globally. As the prevalence of obesity continues to rise, the incidence of GDM is anticipated to increase as well. Despite the significant impact of GDM on maternal and neonatal health, research examining the independent associations between GDM and adverse outcomes remains limited in the U.

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Article Synopsis
  • Gestational diabetes mellitus (GDM) can lead to serious complications during pregnancy, and early detection is key to improving outcomes.
  • A study conducted in Nigeria aimed to evaluate the necessity of early GDM screening among pregnant women in two hospitals, enrolling 270 participants for the analysis.
  • Findings revealed that 7.8% of women were diagnosed with GDM, with a notable prevalence among older and obese participants, highlighting an increased risk among those with a family history of diabetes.
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Perinatal transmission of hepatitis B virus (HBV) and its associated immune escape mutants (IEMs), is the major vehicle through which a population of chronically infected people who serve as infectious HBV reservoirs is maintained in communities. Therefore, to assess the risk of perinatal transmission, 272 pregnant women attending ante-natal clinics in Ibadan metropolis, southwestern, Nigeria, were screened for HBsAg using ELISA technique. Samples positive for HBsAg were subjected to HBV DNA detection by PCR amplification of the S-gene and amplicon sequencing.

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