Publications by authors named "Deborah M Amodie"
The cornerstones of diagnosis of heartworm (HW) in dogs are the detection of circulating antigen from adult female or the visualization of microfilariae in whole blood. These tests are less sensitive in cats because of the feline immune response leading to low numbers of adult worms, but heartworm antibody tests are also licensed for use in cats. HW antibodies in cats are detectable when there has at least been larval development in the tissues, but positive antibody tests cannot distinguish between current and previous larval infections; thus, cats with positive antibody test results are considered currently or previously infected with .
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- The main methods for diagnosing heartworm in dogs involve detecting specific antigens from adult female worms or spotting microfilariae in blood, while these tests are less effective in cats due to their immune response.
- In a study analyzing stray dogs and cats, it was found that 28% of dogs had adult heartworm infections, compared to only 4% of cats, highlighting a significantly higher risk for dogs.
- Despite this difference, about 19% of cats exhibited some level of heartworm infection, suggesting that heartworm prevention is still important for cats living in areas where heartworm transmission is common.
Objective: To determine the effects of 2 doses of recombinant human bone morphogenetic protein-2 in an absorbable collagen sponge (rhBMP-2/ACS) on bone healing in dogs.
Animals: 27 adult dogs.
Procedures: Dogs underwent a mid-diaphyseal (1-mm) tibial osteotomy (stabilized with external skeletal fixation) and received an ACS containing 0.