Publications by authors named "Deborah Kirby"

A fast and accurate averaging method was derived and developed for the analysis and design of quartz phononic frequency combs. The phononic frequency combs were obtained from a pair of coupled nonlinear Duffing equations for quartz resonators by solving the equations in the time domain and performing a fast Fourier transformation (FFT) of the steady-state vibrations of the time series. Noise simulations were added to the drive frequency to study noise transfer characteristics between the drive signal and the resonances of the phononic frequency combs produced in 100-MHz quartz shear-mode resonators.

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We report on a 32-MHz quartz temperature compensated crystal oscillator (TCXO) fully integrated with commercial CMOS electronics and vacuum packaged at wafer level using a low-temperature MEMS-after quartz process. The novel quartz resonator design provides for stress isolation from the CMOS substrate, thereby yielding classical AT-cut f/T profiles and low hysteresis which can be compensated to < ±0.2 parts per million over temperature using on-chip third-order compensation circuitry.

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Incremental piezoelectric equations for small vibrations superposed on initial deformations are presented. The equations are implemented in COMSOL finite element models (FEA). Equations are validated by comparing the results for the force sensitivity coefficient Kf of a circular quartz plate subjected to a pair of diametrical forces with measured data.

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A double-blind, placebo-controlled, four-way crossover study was conducted in 40 subjects to assess the effect of linezolid on corrected QT (QTc) interval prolongation. Time-matched, placebo-corrected QT intervals were determined predose and at 0.5, 1 (end of infusion), 2, 4, 8, 12, and 24 h after intravenous dosing of linezolid 600 and 1,200 mg.

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