Publications by authors named "Deborah J Radcliffe"
Article Synopsis
- The primary goal of growth hormone (GH) treatment is to improve the quality of life (QOL) for both adults and children, alongside other benefits like better metabolic status and growth.
- Despite evidence suggesting GH treatment can enhance QOL in GH-deficient adults, interpretations are complicated by varying definitions, measures, and potential biases in data collection.
- In children, while there is an expectation that GH treatment will improve QOL, especially for those with classical GH deficiency, concrete evidence is limited, particularly for those with idiopathic short stature, highlighting the need for more targeted research and economic analysis of treatment outcomes.
Context: Use of growth hormone (GH) therapy to promote growth in children with idiopathic short stature is controversial. A fundamental issue underlying the controversy is uncertainty about the magnitude of effectiveness of GH for this condition.
Objective: To determine the effect of GH on short- and long-term growth in idiopathic short stature.