Publications by authors named "Deborah Ellames"
Article Synopsis
- Incorporating spirometry into low-dose CT lung cancer screenings can help identify individuals with undiagnosed chronic obstructive pulmonary disease (COPD), although the effects of this approach are not fully understood.
- A study involving 2,391 participants found that 8.4% met criteria for referral to a respiratory team, with a significant number receiving new COPD diagnoses and treatments after further assessment.
- The research underscores the need for accurate postbronchodilator spirometry tests to confirm airflow obstruction before diagnosing and treating COPD, while also revealing challenges in using these screening results effectively.
Introduction: Surgery is the standard of care for early-stage lung cancer, with stereotactic ablative body radiotherapy (SABR) a lower morbidity alternative for patients with limited physiological reserve. Comparisons of outcomes between these treatment options are limited by competing comorbidities and differences in pre-treatment pathological information. This study aims to address these issues by assessing both overall and cancer-specific survival for presumed stage I lung cancer on an intention-to-treat basis.
View Article and Find Full Text PDFIntroduction: The aim of this study was to develop and validate a simple prognostic scoring system using readily available clinical and pathological variables that could stratify patients according to the risk of death following lung cancer resection. We hypothesized that by using additional pathological variables not accounted for by pathological stage alone coupled with markers of overall fitness a new prognostic tool could be developed.
Methods: Multivariable logistic regression analysis of pathological and other clinical variables from patients undergoing surgical resection of non-small cell lung cancer (NSCLC) were used to determine factors independently associated with 2-year overall survival and so derive the scoring system.