Changes in intraocular pressure and pupil size following intramuscular administration of hydromorphone hydrochloride and acepromazine in clinically normal dogs.

Objective: To investigate the effects of intramuscularly administered hydromorphone hydrochloride and acepromazine on intraocular pressure (IOP) and pupil size (PS).

Animals Studied: Seventeen dogs free of clinically relevant ocular abnormalities.

Procedure: Measurements of IOP and PS were obtained and the dogs were injected intramuscularly with hydromorphone (0.