Publications by authors named "Deborah Ancelle"
Article Synopsis
- The study aimed to determine if diabetes is a risk factor for severe COVID-19 outcomes, independent of age and other health conditions, as diabetes is often seen in older individuals.
- Conducted as part of the CORONADO initiative, the research matched 2210 COVID-19 patients with and without diabetes by age, sex, and admission date, assessing outcomes like death and the need for invasive mechanical ventilation.
- Results showed that diabetes patients had higher rates of adverse outcomes within both 7 and 28 days of hospital admission, indicating that diabetes is a significant risk factor for severe COVID-19 complications regardless of age and comorbidity.
Aim: To investigate the association between routine use of dipeptidyl peptidase-4 (DPP-4) inhibitors and the severity of coronavirus disease 2019 (COVID-19) infection in patient with type 2 diabetes in a large multicentric study.
Materials And Methods: This study was a secondary analysis of the CORONADO study on 2449 patients with type 2 diabetes (T2D) hospitalized for COVID-19 in 68 French centres. The composite primary endpoint combined tracheal intubation for mechanical ventilation and death within 7 days of admission.
Article Synopsis
- * Analysis was conducted on 1,965 patients from the CORONADO study, categorizing them into normal weight, overweight, and various obesity classes, revealing significant risks associated with higher BMI for intubation and death by day 7.
- * The findings suggest that while overweight and obesity worsen early COVID-19 prognosis in T2D patients, this negative effect is not observed in patients aged 75 and older, indicating a need for tailored management strategies for older adults.
Objective: Pregnancy in patients with macroprolactinomas has been associated with a higher risk of pituitary tumour growth. However, the incidence and risk factors remain unclear. We aimed to evaluate the evolution of macroprolactinomas during pregnancy and to identify potential risk factors.
View Article and Find Full Text PDFAims: To determine the relationship between early markers of diabetes control and diabetic retinopathy (DR) in type 1 diabetes.
Methods: A historic cohort study was conducted on 712 patients from the CARéDIAB database. HbA and usual metabolic parameters were measured one year after diagnosis of diabetes.
Background: The incidence of childhood type 1 diabetes (T1D) incidence is rising in many countries, supposedly because of changing environmental factors, which are yet largely unknown. The purpose of the study was to unravel environmental markers associated with T1D.
Methods: Cases were children with T1D from the French Isis-Diab cohort.
Background: Pituitary adenomas are rare in children and adolescents. The response of macroprolactinomas to dopamine agonists (DA) in this age group has been less extensively studied than in adults.
Objective: We retrospectively analyzed data on a large cohort of young patients with macroprolactinomas.