Publications by authors named "Debora do Carmo Linhares"
Methicillin-resistant (MRSA) is a multidrug-resistant bacterium with a global presence in healthcare facilities as well as community settings. The resistance of MRSA to beta-lactam antibiotics can be attributed to a mobile genetic element called the staphylococcal cassette chromosome (SCC), ranging from 23 to 68 kilobase pairs in length. The mec gene complex contained in SCC allows MRSA to survive in the presence of penicillin and other beta-lactam antibiotics.
View Article and Find Full Text PDFCathepsin L (CatL) is a lysosomal cysteine protease primarily involved in the terminal degradation of intracellular and endocytosed proteins. More specifically, in humans, CatL has been implicated in cancer progression and metastasis, as well as coronary artery diseases and others. Given this, the search for potent CatL inhibitors is of great importance.
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- Methanotrophic bacteria can utilize methane for energy, playing a crucial role in reducing methane emissions from ecosystems like Brazilian mangroves.
- This study focused on identifying the types and functions of these bacteria in the impacted sediments of Bertioga's mangrove using a method called DNA-based stable isotope probing.
- Results showed that key active microorganisms included Methylomonas and Methylobacter, suggesting a complex interaction in a methane-derived food chain, and pointed to a potential adaptation where some bacteria might perform methane oxidation even in low oxygen conditions.