Publications by authors named "Debora Silveira"

The aim of this study was to identify the main diseases related to trigger finger. A retrospective, observational study was performed with data obtained through a computerized record of 75 patients with trigger finger diagnosis between July 2011 and October 2015. The diagnosis of metabolic syndrome was performed following National Cholesterol Education Program Adult Treatment Panel III (2001).

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The present study aimed to investigate the presence of Vibrio vulnificus in fish captured at the Lagoa dos Patos estuary (RS, Brazil), to establish a correlation between bacterial biofilm formation and sublethal stress, and to assess the resistance of the isolates to antimicrobials and sanitizers. A total of 217 isolates characteristic of Vibrio sp. were analyzed.

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Article Synopsis
  • The study investigates the effectiveness of stress echocardiography (SE) for predicting all-cause mortality and major cardiac events (MACE) in patients with intermediate risk for coronary artery disease (CAD) who had normal exercise tests (ET).
  • Out of 397 patients analyzed, those with positive SE indicating myocardial ischemia had a significantly higher risk of MACE, making SE a useful tool for identifying higher-risk patients.
  • Key independent predictors for all-cause mortality included being male and over 60 years of age, highlighting the need for targeted monitoring in these groups even with normal ET results.
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Article Synopsis
  • Chronotropic incompetence (CI) is linked to increased mortality risk and coronary artery disease, yet its underlying mechanisms are unclear.
  • A study analyzed 610 patients undergoing exercise echocardiography, dividing them into two groups based on their heart rate response during the test: those with CI (Chl) and those without (ChC).
  • Findings revealed that patients with CI exhibited more symptoms like dyspnoea and hypertension, poorer exercise tolerance, and significant left ventricle dysfunction, particularly related to severe right coronary artery blockages.
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Background: GH deficiency (GHD) is often associated with cardiovascular risk factors, including abdominal fat accumulation, hypercholesterolemia, and increased C-reactive protein. Despite the presence of these risk factors, adults with congenital lifetime isolated GHD (IGHD) due to an inactivating mutation in the GHRH receptor gene do not have premature atherosclerosis.

Objective: The aim was to study the serum levels of adiponectin and leptin (antiatherogenic and atherogenic adipokine, respectively), and the urinary albumin excretion (UAE) in these IGHD individuals.

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Context: Reduced longevity observed in hypopituitarism has been attributed to GH deficiency (GHD). It is, however, unclear whether GHD or other confounding factors cause this early mortality.

Objective: The aim was to study longevity in subjects from a large kindred with untreated, lifetime isolated GHD (IGHD) due to a homozygous mutation in the GHRH receptor gene and in heterozygous carriers of the mutation.

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Background: Dealing with genetic inconsistencies in parentage testing, especially in motherless cases, remains a continual difficulty.

Study Design And Methods: Four difficult cases, comprising two trios and two duos, were selected from routine parentage testing casework. In these, relatively low combined paternity indices were observed as a result of few discrepant loci that were treated as being due to paternal mutations.

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