Publications by authors named "Debora Sant' Anna"
Ancestry and self-reported race in Brazilian breast cancer women.
Rev Assoc Med Bras (1992)
November 2023
Objective: This study aimed to evaluate the association between self-reported race/color and ancestry in Brazilian patients with breast cancer.
Methods: This was an observational, transversal, epidemiological study, evaluating race and ancestry in 1,127 patients with breast cancer. For genetic ancestry, a 46-AIM-INDEL panel was used.
Article Synopsis
- The study investigates how breast cancer molecular subtypes vary among Brazilian women based on their genetic ancestry and ethnicity, identifying distinct differences across different regions of Brazil.
- 1127 breast cancer patients were analyzed, revealing that those in the South had higher European ancestry and were more likely to have HER-2 luminal tumors, while those in the North and Northeast had higher African ancestry and more aggressive triple-negative tumors.
- The findings underscore the importance of genetic ancestry and ethnicity in understanding breast cancer characteristics, which could enhance early diagnosis and treatment strategies in Brazil.*
Introduction: TP53 is the most frequently mutated gene in lung tumors, but its prognostic role in admixed populations, such as Brazilians, remains unclear. In this study, we aimed to evaluate the frequency and clinicopathological impact of TP53 mutations in non-small cell lung cancer (NSCLC) patients in Brazil.
Methods: We analyzed 446 NSCLC patients from Barretos Cancer Hospital.
The applicability of gene sequencing and MALDI-TOF to identify less common gram-negative rods (Advenella, Castellaniella, Kaistia, Pusillimonas and Sphingobacterium) from environmental isolates.
Antonie Van Leeuwenhoek
February 2020
Our aim was to identify less common non-fermenting gram-negative rods during the bioremediation process. Five genera were found: Advenella, Castellaniella, Kaistia, Pusillimonas and Sphingobacterium, for a total of 15 isolates. Therefore, we evaluated the applicability of four methods currently available for bacteria identification: (1) conventional biochemical methods, (2) the VITEK-2 system, (3) MALDI-TOF mass spectrometry and (4) 16S rRNA gene sequencing.
View Article and Find Full Text PDFSewage sludge (SS) obtained after sewage treatment process may contain several toxic substances. Bioremediation can decrease the toxicity of the sludge, mainly when it is associated with stimulant agents, such as sugarcane bagasse (B). Samples of pure SS (SSP); SS+B; SS+Soil; and SS+B+Soil were bioremediated for 1, 3, and 6 months (T1, T2, and T3, respectively).
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