Growth kinetics and fitness of fluoroquinolone resistant and susceptible strains of cattle origin.

Human enterocolitis is frequently caused by the Gram-negative microaerobic bacterium . Macrolides (e.g.

Influence of Single Dose Enrofloxacin Injection on Development of Fluoroquinolone Resistance in in Calves.

Fluoroquinolone (FQ) resistance in a major foodborne bacterial pathogen, , derived from cattle has recently become prevalent and poses a significant public health concern. However, the underlying factors for this increase are not entirely clear. To evaluate the effect of enrofloxacin treatment on FQ-resistance development in , 35 commercial calves were equally divided into five groups (Groups 1-5) and were orally inoculated with FQ-susceptible (FQ-S) .

Mastitis in Dairy Cattle: Etiology, Diagnosis, and Treatment Challenges.

Bovine mastitis is an inflammation of the udder tissue parenchyma that causes pathological changes in the glandular tissue and abnormalities in milk leading to significant economic losses to the dairy industry across the world. Mammary pathogenic (MPEC) is one of the main etiologic agents of acute clinical mastitis in dairy cattle. MPEC strains have virulence attributes to resist the host innate defenses and thrive in the mammary gland environment.

Effect of Danofloxacin Treatment on the Development of Fluoroquinolone Resistance in in Calves.

is a leading cause of foodborne gastroenteritis. Recent studies have indicated a rise in fluoroquinolone-resistant (FQ-R) in cattle, where FQ is used to control bovine respiratory disease (BRD). To assess the effect of danofloxacin treatment on the development of FQ-resistance in , 30 commercial calves were divided into Group 1, Group 2, and Group 3 ( = 10), and were all inoculated orally with FQ-susceptible (FQ-S) ; seven days later, Group 3 was challenged with transtracheal , and one week later, Group 2 and Group 3 were injected subcutaneously with danofloxacin.

Distribution of CRISPR Types in Fluoroquinolone-Resistant Isolates.

To aid development of phage therapy against , we investigated the distribution of the clustered regularly interspaced short palindromic repeats (CRISPR) systems in fluoroquinolone (FQ)-resistant . A total of 100 FQ-resistant strains from different sources were analyzed by PCR and DNA sequencing to determine resistance-conferring mutation in the gene and the presence of various CRISPR systems. All but one isolate harbored 1-5 point mutations in and the most common mutation was the Thr86Ile change.

Prevalence of Colistin Resistance in in Eastern Turkey and Genomic Characterization of an Positive Strain from Retail Chicken Meat.

Colistin is one of the most effective antibiotics against multidrug resistant Gram-negative bacteria. However, the recent emergence of plasmid-borne mobilized colistin resistance () genes is considered a serious antimicrobial resistance challenge worldwide. In this study, we report detection of an carrying isolate (named ATAVET -1 Turkey) from retail raw chicken meat in Turkey.