Publications by authors named "Debora Familiar Rodrigues Macedo"
Braz J Microbiol
December 2022
Article Synopsis
- The study investigates the effectiveness of using oral fluid (OF) samples for diagnosing and characterizing parvovirus B19 genotypes during erythema infectiosum outbreaks, where previous research focused mainly on serological diagnosis.
- Using paired serum and oral fluid samples from patients, researchers found that quantitative PCR (qPCR) was more effective than conventional PCR (cPCR) for detecting B19-DNA, although OF samples generally had a lower viral load compared to serum.
- The research highlights that while PCR-based methods may miss about 50% of B19-DNA in OF samples compared to serum, analyzing the genome from these non-invasive samples can provide valuable insights into the genetic diversity of circulating B19 strains.
