Unmasking of infra-Hisian conduction abnormality by intravenous isoproterenol during electrophysiology study for syncope.

Recurrent unexplained syncope in the background of bundle branch block (BBB) often requires a pacemaker. But the decision-making for pacemaker is difficult in case of single episode of syncope with intermittent bundle branch block. We encountered one such case with intermittent LBBB, where the results of invasive EP study were even normal, until intravenous isoproterenol unmasked the infra-Hisian disease during decremental atrial pacing.

A study of platelet aggregation in patients with acute myocardial infarction at presentation and after 48 hrs of initiating standard anti platelet therapy.

Aims & Objectives: Platelet aggregation is a key factor behind coronary artery disease. Various complications after an attack of acute coronary syndrome are often related to the platelet hyperactivity in the early hours following the event. There is a growing concern regarding aspirin & clopidogrel resistance, which has put the time-tested therapies under scrutiny.