Colonisation with Staphylococcus aureus and Streptococcus pyogenes in New Zealand preschool children.

Aim: To describe colonisation patterns of Staphylococcus aureus (S. aureus) and Streptococcus pyogenes (S. pyogenes) among pre-school children in New Zealand.

Tumor and normal tissue dosimetry changes during MR-guided pulsed-dose-rate (PDR) brachytherapy for cervical cancer.

Background And Purpose: To analyze systematic changes in tumor and normal tissue anatomy and dosimetry using serial MR imaging during pulsed dose rate brachytherapy (PDR BT) for cervical cancer.

Material And Methods: Forty-three patients with cervical cancer underwent MR-guided PDR BT using an intrauterine applicator alone after external beam radiotherapy. MR imaging was repeated on days 2 and 3 of treatment and the day 1 plan was applied to the re-contoured volumes.

Beyond tamoxifen: extended and late extended endocrine therapy in postmenopausal early breast cancer.

Breast cancer is a leading cause of cancer death among women worldwide. The majority of cases are oestrogen receptor- or progesterone receptor-positive and, therefore, potentially sensitive to endocrine therapy. A significant risk of recurrence and death persists following initial diagnosis, with over one half of all recurrences and two thirds of breast cancer-related deaths reported to occur following completion of standard adjuvant tamoxifen therapy.

Celiac disease.

Clinically, celiac disease has always been regarded as a wasting, malabsorptive disorder due to disease of the small intestinal mucosa. It has been difficult for clinicians to recognize that this condition is primarily due to sensitization of mesenteric T lymphocytes to wheat protein (gluten) in genetically predisposed (DQ2+) individuals. On contact with dietary-derived gluten in the upper intestine, these sensitized T lymphocytes are activated leading to inflammation of and morphologically altered mucosal architecture: the latter reverts to normal with a gluten-free diet.