Publications by authors named "Debbie Ryan"
Objectives: This multicenter cohort study describes Aotearoa New Zealand children hospitalized during the country's first wave of sustained SARS-CoV-2 transmission, Omicron variant.
Methods: Children younger than 16 years, hospitalized for >6 hours with COVID-19 across New Zealand from January to May 2022 were included. Admissions for all Māori and Pacific and every second non-Maori non-Pacific children were selected to support equal explanatory power for ethnic grouping.
Background: The Census of Populations and Dwellings' is the five yearly population count of Aotearoa New Zealand. Best available populations (BAP) are subnational projections based on census data and demographic assumptions developed for healthcare planning and funding allocation but are also used as the denominator for health indicator monitoring. Pacific people are systematically undercounted, but the impact on health statistics is not well studied.
View Article and Find Full Text PDFBackground: After COVID-19 arrived in New Zealand, a national system was developed to improve the efficiency of contact tracing. The first outbreak was followed by a period of 'COVID-19 elimination', until a community outbreak occurred in August 2020. We describe the characteristics of cases and their contacts during this outbreak, focused on the results of contact tracing.
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- * This study explored the effects of a heterologous vaccine boost in two CLL patients who had inadequate responses to their initial mRNA vaccinations.
- * Results showed that one patient developed strong immune responses, including antibodies and specific T-cells, while the other did not, indicating that a third dose could enhance immune response in some CLL patients who initially struggled.
Article Synopsis
- CLL patients often face severe immune dysfunction, making standard COVID-19 vaccines less effective, prompting the exploration of a heterologous boost for those who didn't respond to the initial vaccine series.
- Two CLL patients were observed in a study after receiving a third dose of a different COVID-19 vaccine (Ad26.COV2.S) to assess their immune response.
- Following this third dose, one patient showed a positive immune response with significant antibody and T-cell production, while the other did not demonstrate similar improvements.
The purpose of the New Zealand Child and adolescent asthma guidelines: a quick reference guide is to provide simple, practical, evidence-based recommendations for the diagnosis, assessment and management of asthma in children and adolescents in New Zealand, with the aim of improving outcomes and reducing inequities. The intended users are health professionals responsible for delivering asthma care in the community and hospital emergency department settings, and those responsible for the training of such health professionals.
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