Publications by authors named "Debbi Poles"

Article Synopsis
  • Prevention of ABO-incompatible red cell transfusions (ABO-it) relies on precise identification of donors and patients, with different practices in France, Germany, and the UK.
  • A study analyzed ABO-it incidents from 2013 to 2022 and found similar average frequencies of ABO-it in France (0.19) and the UK (0.28), but a higher rate in Germany (0.71), despite similar safety measures.
  • The main causes of ABO-it were errors in patient identification and administering the wrong red cell unit, highlighting the need for improved identification systems and processes to enhance transfusion safety.
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Background: Effective transfer of information relating to patient care is vital in healthcare. In the UK formal handover is an established and well reported process in the clinical setting but less so in transfusion laboratories. Blood transfusions occur within many hospital specialities and across clinical and laboratory staff shifts, making robust handover critical for safe practice.

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Background: Irradiation of cellular blood components is recommended for patients at risk of transfusion-associated graft-vs-host disease (TA-GvHD). Prestorage leucodepletion (LD) of blood components is standard in the UK since 1999.

Study Design And Methods: Analysis of 10 years' reports from UK national hemovigilance scheme, Serious Hazards of Transfusion (2010-2019), where patients failed to receive irradiated components when indicated according to British Society for Haematology guidelines (2011).

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Objectives: To establish, in an unselected population of London haemoglobinopathy patients, transfusion requirements, blood antigens/alloantibodies, transfusion modalities, burden of transfusion reactions and donor exposure.

Background: Haemoglobinopathy patients are among the most highly transfused patient populations, and the overall population and number of patients on long-term transfusion programmes are increasing. To provide a safe and efficacious transfusion service for patients, it is important to understand current practice, morbidity associated with transfusion, efficacy of different transfusion modalities and geno-/phenotype requirements.

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Background: Errors in hospital transfusion may cause wrong (blood) components to be transfused. This study assessed the value of electronic identification systems (EISs) in reducing wrong component transfusions (WCTs).

Methods: UK hospitals reporting to Serious Hazards of Transfusion were invited to complete an electronic survey about transfusion including the use of EISs.

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