Publications by authors named "Debarghya Nandi"

Article Synopsis
  • Kenya saw an increase in mental health issues, sexual activity, and pregnancies among schoolgirls due to school closures during COVID-19.
  • The study analyzed data from 436 secondary schoolgirls to explore how COVID-19 stress affected risks for reproductive tract infections like bacterial vaginosis (BV) and sexually transmitted infections (STIs).
  • Findings revealed that the prevalence of BV and STIs rose significantly during the pandemic, attributed to increased stress affecting mental health and feelings of safety, leading to higher sexual exposure.
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Article Synopsis
  • The study investigates the impact of COVID-19 on the mental health and sexual behavior of girls in rural Kenya, focusing on how increased stress during the pandemic might influence the risk of reproductive tract infections like bacterial vaginosis (BV) and sexually transmitted infections (STIs).
  • Data collected from 436 secondary school girls showed a significant increase in both BV and STI prevalence during the COVID period compared to before, with BV rising from 12.1% to 24.5% and STIs from 10.7% to 18.1%.
  • The research found that higher levels of COVID-related stress correlated with increased depressive symptoms and a decreased sense of safety at home, which were
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Article Synopsis
  • Sexually transmitted diseases (STDs) affect about 1 in 5 people yearly and discussions about them on platforms like Reddit can provide valuable insights, especially during events like the COVID-19 pandemic.
  • This study analyzed over 24,000 Reddit posts from March 2019 to July 2021, using topic modeling to identify themes in STD-related discussions over time.
  • Findings showed that while certain discussion topics remained consistent, their prevalence changed with time, reflecting the impact of the pandemic on STD symptoms, testing behaviors, and user experiences.
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Background: Penile microbiome composition has been associated with HSV-2 and HIV in men and with bacterial vaginosis (BV) and HSV-2 in female sex partners. This study sought to 1) characterize penile microbiome composition over a 1-year period and 2) identify factors associated with penile microbiome composition over time.

Methods: This prospective study of community-recruited heterosexual couples in Kenya measured penile and vaginal microbiomes 16S ribosomal RNA gene amplicon sequencing at 4 time points over 1 year (1, 6, and 12 months after baseline).

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Background: We determined how the vaginal and penile microbiomes contribute to herpes simplex virus type 2 (HSV-2) serostatus within sexual partnerships.

Methods: Microbiomes were characterized in cervicovaginal lavage and penile meatal swab specimens through high-throughput 16s ribosomal RNA gene amplicon sequencing. HSV-2 antibody was detected in serum specimens.

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