Spatiotemporally Controlled Release of Etamsylate from Bioinspired Peptide-Functionalized Nanoparticles Arrests Bleeding Rapidly and Improves Clot Stability in a Rabbit Internal Hemorrhage Model.

Achieving rapid clotting and clot stability are important unmet goals of clinical management of noncompressible hemorrhage. This study reports the development of a spatiotemporally controlled release system of an antihemorrhagic drug, etamsylate, in the management of internal hemorrhage. Gly-Arg-Gly-Asp-Ser (GRGDS) peptide-functionalized chitosan nanoparticles, with high affinity to bind with the GPIIa/IIIb receptor of activated platelets, were loaded with the drug etamsylate (etamsylate-loaded GRGDS peptide-functionalized chitosan nanoparticles; EGCSNP).

Biomaterials-Based Strategies to Enhance Angiogenesis in Diabetic Wound Healing.

Amidst the present healthcare issues, diabetes is unique as an emerging class of affliction with chronicity in a majority of the population. To check and control its effects, there have been huge turnover and constant development of management strategies, and though a bigger part of the health care area is involved in achieving its control and the related issues such as the effect of diabetes on wound healing and care and many of the works have reached certain successful outcomes, still there is a huge lack in managing it, with maximum effect yet to be attained. Studying pathophysiology and involvement of various treatment options, such as tissue engineering, application of hydrogels, drug delivery methods, and enhancing angiogenesis, are at constantly developing stages either direct or indirect.

A systematic literature review of cybersecurity scales assessing information security awareness.

Information Security Awareness (ISA) is a significant concept that got considerable attention recently and can assist in minimizing the risks associated with information security breaches. Several measurement scales have been developed in this regard, as measuring users' ISA is paramount. Although ISA specific scales are very important, yet what methodological rigor they use in terms of initial conceptualization of ISA, data collection and analysis during the development, and scale validation of such scales are some unknown aspects.

A Systematic Review of Voice Assistant Usability: An ISO 9241-11 Approach.

Voice assistants (VA) are an emerging technology that have become an essential tool of the twenty-first century. The VA ease of access and use has resulted in high usability curiosity in voice assistants. Usability is an essential aspect of any emerging technology, with every technology having a standardized usability measure.

The effect of trust and its antecedents towards determining users' behavioral intention with voice-based consumer electronic devices.

Advances in artificial intelligence (AI) have ushered in a new era of consumer electronic (CE) devices: the voice-based CE devices (VCED's). A striking feature that separates these from other CE devices are their anthropomorphic capabilities. While current CE research has given a strong focus on improving various technical and security aspects of the VCED's, not much efforts have been given to explore their diffusion and acceptance in the society.

Usability Evaluation of Artificial Intelligence-Based Voice Assistants: The Case of Amazon Alexa.

Currently, the use of voice-assistants has been on the rise, but a user-centric usability evaluation of these devices is a must for ensuring their success. System Usability Scale (SUS) is one such popular usability instrument in a Graphical User Interface (GUI) scenario. However, there are certain fundamental differences between GUI and voice-based systems, which makes it uncertain regarding the suitability of SUS in a voice scenario.

Perceived usability evaluation of Microsoft Teams as an online learning platform during COVID-19 using system usability scale and technology acceptance model in India.

The COVID-19 pandemic has resulted in a physical shutdown of all types of educational institutes worldwide due to which the education delivery has now shifted to an "" exclusivity model. In this perspective, perceived usability of the online learning platforms that are currently being used is an important aspect, especially due to the absence of any physical classes. In this work Microsoft Teams is used as the reference platform for which the perceived usability is evaluated.