Dose equivalence for metaraminol and noradrenaline - A retrospective analysis.

Background: Noradrenaline and metaraminol are commonly used vasopressors in critically ill patients. However, little is known of their dose equivalence.

Methods: We conducted a single centre retrospective cohort study of all ICU patients who transitioned from metaraminol to noradrenaline infusions between August 26, 2016 and December 31, 2020.

Early solar system. Stellar origin of the ¹⁸²Hf cosmochronometer and the presolar history of solar system matter.

Among the short-lived radioactive nuclei inferred to be present in the early solar system via meteoritic analyses, there are several heavier than iron whose stellar origin has been poorly understood. In particular, the abundances inferred for (182)Hf (half-life = 8.9 million years) and (129)I (half-life = 15.