Publications by authors named "Dean Mastras"
Purpose: The noninvasive image-guided breast brachytherapy (NIBB) technique is a novel noninvasive yet targeted method for accelerated partial breast irradiation. We established a multi-institutional registry to evaluate the toxicity and efficacy of this technique across various practice settings.
Methods And Materials: Institutions using the NIBB technique were invited to participate.
Article Synopsis
- Noninvasive image guided breast brachytherapy (NIBB) is a novel, non-invasive method for delivering accelerated partial breast irradiation (APBI) that uses breast compression and imaging for high precision without large tumor volume margins.* -
- In a phase 2 study involving 40 patients, aged 68 on average, treatment involved delivering a total dose of 34 Gy in 10 fractions, where late toxicity was minimal, with only 5% and 10% reporting grade 2 toxicity at 2 and 5 years, respectively.* -
- Results showed a 95% good to excellent cosmetic outcome at 2 years, a 100% rate at 5 years, and a 93.3%
Purpose: Noninvasive image-guided breast brachytherapy (NIBB) is a novel approach to deliver accelerated partial breast irradiation (APBI). NIBB is noninvasive, yet maintains a high degree of precision by using breast immobilization and image guidance. This makes NIBB an attractive alternative to existing APBI techniques.
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