Contrasting Direct Instruction in Morphological Decoding and Morphological Inquiry-Analysis Interventions in Grade 3 Children With Poor Morphological Awareness.

We report on a school-based randomized control trial study comparing two morphological interventions with untaught controls: one focusing on direct instruction targeting print morphological decoding (direct decoding condition) and the other on inquiry-focused pedagogy using oral morphological analysis (inquiry-analysis condition). We identified 63 Grade 3 children with below-average morphological awareness following screening (from = 163). This sub-sample showed average pseudoword decoding but poor language and word reading abilities.

Effects of mandatory homeschooling during COVID-19 on conflict in romantic couples.

In early 2020, schools across Canada closed due to the COVID-19 pandemic, requiring parents to homeschool their children. We examined the association between homeschooling and romantic conflict among couples during the COVID-19 pandemic. Canadian couples ( = 756) completed online measures, including whether they were homeschooling, hours spent homeschooling, and romantic conflict during the month of April 2020.

The missing-colour effect: The attentional beam captures reading-relevant and reading-irrelevant information.

According to many models, reading is driven by an attentional beam. In two experiments, we investigated the specificity of the beam by testing its sensitivity to a reading-irrelevant feature: colour. More specifically, participants were asked to read either a black-and-white version or a multi-colour version of the text in which each letter was printed in a different colour.

Muscle-Specific Sensitivity to Voluntary Physical Activity and Detraining.

Aerobic physical activity triggers adaptations in skeletal muscle including a fast-to-slow shift in myosin heavy chain (MHC) isoforms, an enhanced capillary network, and mitochondrial biogenesis to meet increased demands placed upon this tissue. Although the magnitude of these responses appears to be dependent on muscle phenotype as well as training volume and/or intensity, the whole-muscle response to detraining remains mostly unexplored. Here, we hypothesized that the shifts toward slower MHC phentotype and the increased capillarity and mitochondrial oxidative markers induced with training would return toward sedentary (SED) control levels sooner in the fast plantaris than in the slow soleus muscle as a result of detraining.

From Cantonese Lexical Tone Awareness to Second Language English Vocabulary: Cross-Language Mediation by Segmental Phonological Awareness.

Purpose Cantonese lexical tone awareness is closely associated with 1st language Cantonese vocabulary knowledge, but its role in 2nd language English vocabulary knowledge was unclear. We addressed this issue by investigating whether and, if so, how Cantonese lexical tone awareness contributes to English expressive vocabulary knowledge in Hong Kong Cantonese-English bilingual children. Method A sample of 112 Hong Kong Cantonese-English bilingual 2nd graders were tested on Cantonese lexical tone awareness, English lexical stress sensitivity, Cantonese- English segmental phonological awareness, and both Cantonese and English expressive vocabulary knowledge.

Ages for the Middle Stone Age of southern Africa: implications for human behavior and dispersal.

The expansion of modern human populations in Africa 80,000 to 60,000 years ago and their initial exodus out of Africa have been tentatively linked to two phases of technological and behavioral innovation within the Middle Stone Age of southern Africa-the Still Bay and Howieson's Poort industries-that are associated with early evidence for symbols and personal ornaments. Establishing the correct sequence of events, however, has been hampered by inadequate chronologies. We report ages for nine sites from varied climatic and ecological zones across southern Africa that show that both industries were short-lived (5000 years or less), separated by about 7000 years, and coeval with genetic estimates of population expansion and exit times.

The representation of morphologically complex words in the developing lexicon.

The study reported here examined the manner in which children represent morphologically complex words in the lexicon. Children in grades 1 to 5 completed a fragment completion task to assess the priming effects of morphologically related words. Both inflected and derived words (e.

Human foot bones from Klasies River main site, South Africa.

The caves at Klasies River contain abundant archaeological evidence relating to human evolution in the late Pleistocene of southern Africa. Along with Middle Stone Age artifacts, animal bones, and other food waste, there are hominin cranial fragments, mandibles with teeth, and a few postcranial remains. Three foot bones can now be added to this inventory.

Mineral wealth and medical opportunity.

With the increase in population and in colonial revenues after the discovery of diamonds and gold in the last quarter of the nineteenth century, public and private hospitals proliferated, particularly in larger centres such as Cape Town. The numbers of practitioners engaged in public health also increased. Perhaps as important, doctors were now accepted as skilled professionals and remunerated accordingly.

Opportunities outside private practice before 1860.

This chapter discusses the restrictions and opportunities which salaried employment offered Cape doctors in the pay of government and charitable organisations during the first two thirds of the nineteenth century. Although Cape doctors often acted as agents of the colonial state there were many nuances within this relationship. While military doctors played an important role in the profession during the first few decades of the century, by the 1840s civilian doctors were beginning to assert greater influence in Cape Town, if not yet in the Eastern Cape.

Medical gentlemen and the process of professionalisation before 1860.

In the early-nineteenth century, the professionalisation of medicine at the Cape began in earnest. Although there were key legislative and professional developments in this period, the notion, outlined in Burrows' seminal work on South African medical history, that it was a 'golden' age of medical reform underplays the extent of intra-professional differentiation and draws attention away from the politics of professional regulation at the Cape. The period was a time of inter- and intra-professional conflict as doctors, druggists and shopkeepers competed to sell drugs and medical advice and it spawned a profession that was deeply divided.

The Cape doctor and the broader medical market, 1800-1850.

Regularly trained and licensed Cape doctors in the nineteenth century operated within a medical market which accommodated other suppliers of medical care, both competing and complementary. These 'alternative practitioners' included shopkeepers selling patent medicines, apothecaries, chemists and midwives, Muslim folk healers and indigenous Khoisan or African healers. Licensed doctors also provided medical services for a wide variety of clients - white settlers, their slaves, servants, free blacks and indigenes, usually in decreasing order of frequency.

Introduction: the Cape Doctor in the nineteenth century.

The Cape Doctor, named after the profession as well as the wind that sweeps the Cape Peninsula of dangerous miasmas, is a social history of medicine, seeking to place formal western medicine within its political, social and economic context. Besides Shula Marks' study of South African nurses, Divided Sisterhood, no previous work has brought such a breadth of material about South Africa's medical past under the framework of social history. This work provides clear evidence of the way in which the Cape medical profession excluded all but a few women and black practitioners, and discriminated along lines of race, class and gender in their practice, but it also moves beyond the classic revisionist tradition (documenting the emergence of a society divided along lines of race and gender) by providing examples of cultural crossover and medical pluralism.

An assessment of the bioaccumulation of estrone in Daphnia magna.

The bioaccumulation of estrone by Daphnia magna was determined. Direct uptake via the aqueous medium occurred within the first 16 h. A bioconcentration factor of 228 was established over all temporal periods.

Racism and medical science in South Africa's Cape Colony in the mid- to late nineteenth century.

Racism has been a particular focus of the history of Western medicine in colonial South Africa. Much of the research to date has paradoxically interpreted Western medicine as both a handmaiden of colonialism and as a racist gatekeeper to the benefits of Western medical science. This essay suggests that while these conclusions have some validity, the framework in which they have been devised is problematic.

New human teeth from Middle Stone Age deposits at Klasies River, South Africa.

Since 1984, the main site at Klasies River has been re-investigated. Human remains, animal bones and stone artefacts have been collected from the LBS, SAS and other stratigraphic members, and these discoveries help to establish the antiquity of anatomically near-modern populations practicing a Middle Stone Age way of life on the southern coast of Africa. Several teeth found in the lower SAS levels in 1989-1991 can be matched in recent South African populations.

Decreasing oncoprotein 18/stathmin levels reduces microtubule catastrophes and increases microtubule polymer in vivo.

Oncoprotein 18/stathmin (Op18) has been identified recently as a protein which destabilizes microtubules. To characterize the function of Op18 in living cells, we used microinjection of anti-Op18 antibodies or antisense oligonucleotides to block either Op18 activity or expression in interphase newt lung cells. Anti-tubulin staining of cells microinjected with anti-Op18 and fixed 1-2 hours after injection showed an increase in total microtubule polymer.

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor.

A fundamental question in cell biology is how membrane proteins are sorted in the endocytic pathway. The sorting of internalized beta2-adrenergic receptors between recycling endosomes and lysosomes is responsible for opposite effects on signal transduction and is regulated by physiological stimuli. Here we describe a mechanism that controls this sorting operation, which is mediated by a family of conserved protein-interaction modules called PDZ domains.

A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts.

Kinetochores are complex macromolecular structures that link mitotic chromosomes to spindle microtubules. Although a small number of kinetochore components have been identified, including the kinesins CENP-E and XKCM1 as well as cytoplasmic dynein, neither how these and other proteins are organized to produce a kinetochore nor their exact functions within this structure are understood. For this reason, we have developed an assay that allows kinetochore components to assemble onto discrete foci on in vitro-condensed chromosomes.

Cape Town and 'country' doctors in the Cape Colony during the first half of the nineteenth century.

This paper argues that during the 'golden' age of medical reform in the first half of the nineteenth century in the Cape Colony there was significant differentiation within the medical profession which contributed to a slow and uneven process of professionalization in spite of comprehensive and early legal regulation under one licensing body. Differences in permitted practice, settlement patterns, economic and organizational opportunities gave doctors in Cape Town, the colony's biggest and most important city, greater incentives and more scope to develop professional regulation and organization than those in the rest of the colony. A government Ordinance passed in 1807 gave regularly-trained medical practitioners a legal monopoly over medical practice, but did not initially prevent those practising outside Cape Town from selling both medicines and medical advice.