Publications by authors named "DeLeo V"
Article Synopsis
- Phenology, the timing of plant development, is influenced by genetic variation and affects how traits manifest across different seasons, although much remains unknown about its genetic contributions in wild populations.
- Researchers compared germination and flowering time data from controlled experiments with wild plant collection dates to see if genetic variation could predict natural phenology.
- Although there was a weak correlation found between controlled experiments and wild phenology, local collection date variations were not explained by genetic factors, indicating significant environmental influence and potential for rapid plasticity in natural settings.
Article Synopsis
- - The study analyzed contact allergies to peppermint (MP) oil using data from the North American Contact Dermatitis Group, finding that out of 28,128 patients tested, only 161 (0.6%) exhibited an allergic reaction.
- - The majority of allergic patients were female (77%) and over 40 years old (71.4%), with common dermatitis locations being the face (31.7%), hands (17.4%), and generalized areas (18.6%).
- - A significant number (30.4%) experienced strong to extreme reactions, primarily linked to products like oral hygiene items, foods, and lip products; many also had co-reactions with other fragrance allergens, indicating that around 40% of cases
Article Synopsis
- Photoallergic contact dermatitis (PACD) is a hypersensitivity reaction triggered by allergens only when exposed to UV light, requiring photopatch testing (PhotoPT) for diagnosis.* -
- A study from 2009-2020 involving 454 patients revealed that most were women, aged 21-60, and the majority were White; results showed 119 positive tests, predominantly related to sunscreen agents like benzophenones.* -
- Among the diagnosed conditions, approximately 17.2% of patients had PACD, while other diagnoses included allergic contact dermatitis, polymorphous light eruption, and chronic actinic dermatitis, highlighting the need for photopatch testing in these cases.*
Construction workers (CWs) are at risk for occupational contact dermatitis (CD) owing to workplace exposures. Determine the prevalence of occupational allergic CD and characterize common occupational allergens in CWs referred for patch testing in the United States and Canada. Retrospective cross-sectional analysis of patients patch tested by the North American Contact Dermatitis Group from 2001 to 2020.
View Article and Find Full Text PDFThe second part of this CME article discusses sunscreen regulation and safety considerations for humans and the environment. First, we provide an overview of the history of the United States Food and Drug Administration's regulation of sunscreen. Recent Food and Drug Administration studies clearly demonstrate that organic ultraviolet filters are systemically absorbed during routine sunscreen use, but to date there is no evidence of associated negative health effects.
View Article and Find Full Text PDFAs our knowledge of the harmful effects of ultraviolet radiation continues to evolve, sunscreen remains an integral part of a comprehensive photoprotection strategy against multiple endpoints of ultraviolet-mediated damage. Part 1 of this review covers sunscreen active and additive ingredient properties, mechanisms of action and gaps in coverage. Following an overview of sunscreen's efficacy in protecting against sunburn, photocarcinogenesis, photoaging, pigmentary disorders, and idiopathic photodermatoses, we highlight considerations for product use and selection in children and individuals with skin of color.
View Article and Find Full Text PDFAim: Patterns of individual variation are key to testing hypotheses about the mechanisms underlying biogeographic patterns. If species distributions are determined by environmental constraints, then populations near range margins may have reduced performance and be adapted to harsher environments. Model organisms are potentially important systems for biogeographical studies, given the available range-wide natural history collections, and the importance of providing biogeographical context to their genetic and phenotypic diversity.
View Article and Find Full Text PDFDoubtful patch test reactions generally do not meet criterion for positivity in patch testing. However, the North American Contact Dermatitis Group (NACDG) allows for doubtful reactions to be coded with a final determination of "allergic/positive" based on the temporal pattern, appearance, known characteristics of the allergen, and/or other supportive patch test reactions. To analyze NACDG data from the 2019-2020 patch test cycle to identify patterns in the interpretation and relevance of doubtful reactions.
View Article and Find Full Text PDFAllergic contact dermatitis is frequently caused by metals, including multiple metals simultaneously. To assess characteristics and associations of positive and clinically relevant patch test (PT) reactions with solitary and concurrent metal sensitization. A retrospective analysis of PT results for nickel, cobalt, and/or chromium from the North American Contact Dermatitis Group between 2001 and 2018 ( = 43,522).
View Article and Find Full Text PDFBackground: Isothiazolinones are a common cause of allergic contact dermatitis.
Objective: To examine the prevalence of positive patch test reactions to isothiazolinones from 2017-2020 and characterize isothiazolinone-allergic (Is+) patients compared with isothiazolinone nonallergic (Is-) patients.
Methods: Retrospective cross-sectional analysis of 9028 patients patch tested to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) 0.
Northern red oak (Quercus rubra L.) is an ecologically and economically important forest tree native to North America. We present a chromosome-scale genome of Q.
View Article and Find Full Text PDFParaphenylenediamine (PPD) is an aromatic amine dye that may cause allergic contact dermatitis. This study examines the epidemiology of allergic patch test reactions to PPD. This retrospective analysis characterizes individuals tested to PPD (1% petrolatum) by the North American Contact Dermatitis Group (1994-2018).
View Article and Find Full Text PDFChlorhexidine is an antiseptic that may cause allergic contact dermatitis. To describe the epidemiology of chlorhexidine allergy and characterize positive patch test reactions. This retrospective study analyzed patients patch tested to chlorhexidine digluconate 1% aqueous by the North American Contact Dermatitis Group, 2015-2020.
View Article and Find Full Text PDFCobalt is a recognized cause of allergic contact dermatitis (ACD); however, detailed information on patient characteristics, sites, and sources is lacking. The aim of the study is to assess trends in patch test reactions to cobalt and associated patient characteristics, common sources, and body sites affected. The study used a retrospective analysis of adult patients who were patch tested to cobalt by the North American Contact Dermatitis Group between 2001 and 2018 (n = 41,730).
View Article and Find Full Text PDFBenzophenone (BZP)-3 and BZP-4 are ultraviolet (UV) absorbers used in sunscreens and personal care products (PCPs) and may cause allergic contact dermatitis. To characterize positive patch test reactions to BZP-3 (10% in petrolatum [pet]) and BZP-4 (2% pet) in a screening allergen series. Retrospective analysis of patients tested to BZP-3 and BZP-4 was conducted by the North American Contact Dermatitis Group from 2013 to 2020.
View Article and Find Full Text PDFArticle Synopsis
- * Data was collected from several databases and showed that while positivity rates for MCI/MI have decreased in Europe, they have continued to rise in North America, especially for MI.
- * The differing trends in reactions could be linked to earlier and stricter regulations on MI in Europe compared to North America.
Article Synopsis
- An updated understanding of allergic contact cheilitis is necessary, as it shows increasing prevalence across a study period from 2001 to 2018.
- A retrospective analysis of over 43,000 patients revealed that about 4.8% had lips involved in dermatitis, with a notable rise in cases documented in later years.
- The study found high rates of positive allergic reactions among patients with cheilitis, suggesting the importance of including a broader range of allergens in patch testing, especially those beyond standard NACDG screening.
Background: Dermatitis localized to hands (HD), feet (FD), or both hands and feet (HFD) has multiple etiologies, including atopic dermatitis, irritant contact dermatitis, and allergic contact dermatitis. Unfortunately, little is known about clinical differences between patients with HD, FD, and HFD.
Objective: To characterize differences in demographics, etiology, and patch testing results among patients presenting with HD, FD, or HFD referred for patch testing.
Background: Allergic contact dermatitis (ACD) to cobalt is more common in children and adolescents than adults. However, detailed information on sites and sources of cobalt ACD is limited.
Objectives: To assess trends in positive and clinically relevant patch test reactions to cobalt in children and associated patient characteristics, common sources and body sites affected.
Article Synopsis
- - Alkyl glucosides, used in personal care products, were tested for allergic reactions; among 24,097 patients, 2.0% showed positive patch test reactions.
- - Positive reactions were more common in individuals with occupational skin disease, hay fever, atopic dermatitis, and asthma, with most reactions linked to hair and skin cleansing products.
- - Cross-reactivity between decyl and lauryl glucosides was significant, with over 40% of patients sensitive to both types, indicating relevant clinical implications.