In this study, we expanded upon the job demands-resources model to assess the role of employees' vitality as an inner resource for their work engagement and job commitment. To assess vitality and related job resources, we developed an index of vitality outside of work and adapted measures of manager autonomy support and organizational support. For job demands, we measured work stress and predicted that each of these four variables would contribute independently to work-related outcomes.
View Article and Find Full Text PDFResearchers have consistently found a relationship between psychopathy and the use of sexual coercion in samples of males with and without previous sexual arrests (Abbey, Jacques-Tiura, & LeBreton, 2011; Hare, 1991; Hersh & Gray-Little, 1998; Seto & Lalumiere, 2000). Although there is growing recognition that females also engage in sexually coercive behavior, current understanding of female coercion is limited (Bouffard, Bouffard, & Miller, 2015; Cortoni, Hanson, & Coache, 2010; Muñoz, Khan, & Cordwell, 2011). This study examined the relationship between psychopathic traits and sexual coercion tactics among a sample of 558 undergraduate females.
View Article and Find Full Text PDFMost of the focus within the ostracism literature concerns the negative effects on the ostracized and how they cope following ostracism. Research is now beginning to illuminate negative psychological effects for ostracizers, yet no studies to date have examined their coping responses. This study continues this line of inquiry focusing on experiences of going along with ostracism, both by employing a face-to-face interaction and by exploring prosocial versus antisocial coping reactions in ostracizers.
View Article and Find Full Text PDFMuch research has documented the harmful psychological effects of being ostracized, but research has yet to determine whether compliance with ostracizing other people is psychologically costly. We conducted two studies guided by self-determination theory to explore this question, using a paradigm that borrows from both ostracism research and Milgram's classic study of obedience. Supporting our guiding hypothesis that compliance with ostracizing others carries psychological costs, the results of Experiment 1 showed that such compliance worsened mood compared with complying with instructions to include others and with receiving no instructions involving inclusion or exclusion, an effect explained by thwarted psychological needs resulting from ostracizing others.
View Article and Find Full Text PDFIn a fairly short period of time, data envelopment analysis (DEA) has grown into a powerful quantitative, analytical tool for measuring the relative performance of similar organizations. DEA has been successfully applied to traditional service industries such as universities and hospitals as well as to trades as diverse as banking and manufacturing. To the best of our knowledge, however, DEA has not been applied in the academic medicine healthcare setting.
View Article and Find Full Text PDFWhen individuals grow up with autonomy-thwarting parents, they may be prevented from exploring internally endorsed values and identities and as a result shut out aspects of the self perceived to be unacceptable. Given the stigmatization of homosexuality, individuals perceiving low autonomy support from parents may be especially motivated to conceal same-sex sexual attraction, leading to defensive processes such as reaction formation. Four studies tested a model wherein perceived parental autonomy support is associated with lower discrepancies between self-reported sexual orientation and implicit sexual orientation (assessed with a reaction time task).
View Article and Find Full Text PDFWe hypothesized that glucose transporter 12 (GLUT12) is involved in regulation of glucose flux in distal renal tubules in response to elevated glucose. We used the Madin-Darby canine kidney polarized epithelial cell model and neutralizing antibodies to analyze GLUT12 targeting and directional GLUT12-mediated glucose transport. At physiological glucose concentrations, GLUT12 was localized to a perinuclear position.
View Article and Find Full Text PDFMagnetic resonance imaging (MRI) examinations from 18 dogs with a histologically confirmed peripheral nerve sheath tumor (PNST) of the brachial plexus were assessed retrospectively. Almost half (8/18) had a diffuse thickening of the brachial plexus nerve(s), six of which extended into the vertebral canal. The other 10/18 dogs had a nodule or mass in the axilla (1.
View Article and Find Full Text PDFRenal tubular glucose reabsorption is mediated by facilitative glucose transporter (GLUT) proteins and energy-dependent sodium glucose luminal transporters. Glucose transport in the diabetic kidney is upregulated and has been implicated in the pathogenesis of progressive diabetic nephropathy. Hyperglycemia, hypertension, and activation of the renin-angiotensin system are believed important in the development of the disease.
View Article and Find Full Text PDFThe cornerstone of population genetics is a probabilistic understanding of the ultimate fate--survival or extinction--of rare mutations. If a mutation is beneficial, it enables its carrier to reproduce faster than native wild-type individuals. In classic derivations and in the considerable body of research that has followed, "faster" has been defined mathematically to mean "able to produce more surviving offspring per generation.
View Article and Find Full Text PDFBackground: Hypoxia-tolerant human glioma cells reduce oxygen consumption rate in response to oxygen deficit, a defense mechanism that contributes to survival under moderately hypoxic conditions. In contrast, hypoxia-sensitive cells lack this ability. As it has been previously shown that hypoxia-tolerant (M006x, M006xLo, M059K) and -sensitive (M010b) glioma cells express differences in mitochondrial function, we investigated whether mitochondrial DNA-encoded mutations are associated with differences in the initial response to oxygen deficit.
View Article and Find Full Text PDFVet Radiol Ultrasound
October 2002
There is a need for a rapid assay to identify agents that damage mitochondria because the mitochondrion may be an important target for numerous environmental mitotoxins. Certainly at least one chemotherapeutic regimen (CHOP therapy) that includes doxorubicin can induce cardiomyopathy through mitochondrial genotoxicity in cardiac muscle cells. Yeast cells (1.
View Article and Find Full Text PDFJ Vet Intern Med
November 1997
Magnetic resonance imaging (MRI) was performed on 50 dogs with intracranial neoplasia. The following tumor features were assessed: axial origin, location, shape, growth pattern, MRI signal intensity, evidence for edema, and paramagnetic contrast enhancement. Histologic diagnosis included 5 intracranially invading nasal tumors, 7 pituitary tumors, 22 meningiomas, 6 choroid plexus tumors, 7 astrocytomas, 1 ependymoma, and 2 oligodendrogliomas.
View Article and Find Full Text PDFSPECT and associated imaging procedures were used in beagle dogs to (1) evaluate the uptake, distribution, and clearance properties of i.v.-injected 123I IMP (IMP) and 99mTc HMPAO (HMPAO) in the brain, lungs, liver, and kidneys; (2) quantify the acute effects (after 15 sec) of very low doses (0.
View Article and Find Full Text PDFInt J Radiat Oncol Biol Phys
March 1994
Purpose: Normal tissue tolerance of boron neutron capture irradiation using borocaptate sodium (NA2B12H11SH) in an epithermal neutron beam was studied.
Methods And Materials: Large retriever-type dogs were used and the irradiations were performed by single dose, 5 x 10 dorsal portal. Fourteen dogs were irradiated with the epithermal neutron beam alone and 35 dogs were irradiated following intravenous administration of borocaptate sodium.
Borocaptate sodium (Na2B12H11SH) is a potentially useful compound for boron neutron capture therapy of intracranial tumors. Tumor and normal tissue boron concentrations were evaluated in 30 dogs with naturally occurring intracranial tumors after i.v.
View Article and Find Full Text PDFStrahlenther Onkol
January 1993
Irradiation of the canine head following intravenous Na2B12H11SH (BSH) administration has provided useful information concerning the tolerance of skin and brain to the resultant complex form of irradiation. The effect of the boron capture reaction in skin and brain has provided estimates of the influence of the microscopic dosimetry involved. Dogs irradiated with the epithermal beam alone provided valuable insight into the relative biological effectiveness (RBE) of the fast neutron component (> 10 keV) of the epithermal beam.
View Article and Find Full Text PDFBorocaptate sodium (Na2B12H11SH) is a boron-carrying compound under consideration for use in boron neutron capture therapy. The biodistribution of boron from borocaptate sodium administration will partly determine boron neutron capture therapy efficacy and normal tissue radiation tolerance. The biodistribution of boron was determined in 30 dogs with spontaneous intracranial tumors at 2, 6, or 12 hr after intravenous borocaptate sodium infusion.
View Article and Find Full Text PDFJ Am Vet Med Assoc
May 1992
Triple-phase bone scintigraphy was used to evaluate tissue viability in the forelimb of a dog after gunshot injury. This technique was reliable, noninvasive, and easily performed. It was used to complement radiography by providing functional, rather than structural, assessment of tissues on the basis of regional vascular patterns.
View Article and Find Full Text PDFQuantitative electroencephalography was assessed in dogs under controlled, 2% end-tidal isoflurane anesthetic conditions, and each variable at each electrode site was tested for normal distribution. With the quantitative electroencephalographic system used, 16 values for each of 21 electrode sites were evaluated. Absolute power ratios also were evaluated.
View Article and Find Full Text PDFJ Pediatr Psychol
September 1989
Investigated the contribution of disability parameters and chronic disability-related strain to the adaptation of 50 congenitally physically handicapped 6- to 11-year-old children and their mothers. Multiple dimensions of adaptation, disability status, and chronic disability-related strain were assessed with a variety of procedures. The mothers reported their children and themselves to display significantly worse adaptation than expected for a general sample.
View Article and Find Full Text PDFThree groups of college women were compared on the following dimensions: sexual experiences, sexual satisfaction, self-concept, sexual attitudes and knowledge, and parental support for sexual development. Groups were composed of women with late-onset physical disability, early-onset physical disability, and no disability. Measures utilized included an extension of the Sexual Interaction Inventory, the Tennessee Self-Concept Inventory, the Sexual Knowledge and Attitude Test, and questionnaires developed for this study.
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