A privileged role for neuronal Na channels in regulating ventricular [Ca] and arrhythmias.

Jones et al. provide commentary on the intricate crosstalk between ion transporters that goes awry in long QT arrhythmia.

Analysis of copy number loss of the ErbB4 receptor tyrosine kinase in glioblastoma.

Current treatments for glioblastoma multiforme (GBM)-an aggressive form of brain cancer-are minimally effective and yield a median survival of 14.6 months and a two-year survival rate of 30%. Given the severity of GBM and the limitations of its treatment, there is a need for the discovery of novel drug targets for GBM and more personalized treatment approaches based on the characteristics of an individual's tumor.