Publications by authors named "De-zhen Yin"
[Retros Flt-1 decelerates the growth of a murine experimental osteosarcoma].
Zhonghua Wai Ke Za Zhi
August 2011
Objective: To examine the influence of vascular endothelial growth factors (VEGF) in controlling the growth of an experimental osteosarcoma in mice by performing retrovirus-mediated sFlt-1 gene modification.
Methods: From March to October 2010 human osteosarcoma G-292 cells were in vitro infected with retroviral vectors encoding soluble Flt-1 or LacZ gene before transplanted into proximal tibiae of immune deficient SCID mice to establish experimental orthotopic osteosarcoma. Daily observation and biweekly microCT were performed to monitor tumor development and progression till sacrifice at 8 weeks after tumor cell inoculation for histological and molecular analyses.
Article Synopsis
- The study looked at how the height of bone grafts affects the stability of the neck after a surgery called anterior cervical discectomy, which helps with nerve problems.
- They tested six human necks in different conditions using grafts that were 100%, 120%, 140%, and 160% of the normal height.
- The results showed that using grafts taller than normal (140% or 160%) made the neck more stable than using a normal height graft (100%).
Object: Chronic mechanical compression of the spinal cord, which is commonly caused by degeneration of the spine, impairs motor and sensory functions insidiously and progressively. Yet the exact mechanisms of chronic spinal cord compression (SCC) remain to be elucidated. To study the pathophysiology of this condition, the authors developed a simple animal experimental model that reproduced the clinical course of mechanical compression of the spinal cord.
View Article and Find Full Text PDFObjective: To observe the effects of cryopreserved olfactory ensheathing cells (OECs) transplantation on axonal regeneration and functional recovery following spinal cord injury in adult rats.
Methods: Twenty-four rats were divided into experimental and control groups, each group having 12 rats. The spinal cord injury was established by transecting the spinal cord at T10 level with microsurgery scissors.
[Treatment of fracture involved articular surface with absorbable screws and rods].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
November 2003
Objective: To investigate the treatment results of fracture involved articular surface with absorbable screws and rods.
Methods: From October 1995 to May 2002, 32 patients with fracture involved articular surface were treated with absorbable screws and rods with the materials of SR-PGA and SR-PLLA. Bone traction or plaster external fixation were carried out postoperatively.